Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase NA 1Phase 3 1Phase 1/2 1

Status

Completed 12Recruiting 6Active not recruiting 3Unknown 1Terminated 1Not yet recruiting 1

Sponsor Class

OTHER 4NIH 1INDUSTRY 1

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6

Conditions

Prostatic Neoplasms 17Esophageal Neoplasms 9Glioblastoma 8Squamous Cell Carcinoma of Head and Neck 7Rectal Neoplasms 7Oropharyngeal Neoplasms 7Breast Neoplasms 7Mouth Neoplasms 6Glioma 6Triple Negative Breast Neoplasms 4Lung Neoplasms 4Laryngeal Neoplasms 4Head and Neck Neoplasms 4Brain Neoplasms 4Uterine Cervical Neoplasms 3Urinary Bladder Neoplasms 3Stomach Neoplasms 3Sarcoma 3Pancreatic Neoplasms 3Multiple Myeloma 3Neuroblastoma 2Neoplasms 2Nasopharyngeal Carcinoma 2Melanoma 2Medulloblastoma 2Hypopharyngeal Neoplasms 2Ganglioneuroblastoma 2Esophageal Squamous Cell Carcinoma 2Endometrial Neoplasms 2Colorectal Neoplasms 2

Interventions

Magnetic Resonance Spectroscopy 20Temozolomide 16Radiotherapy 10Specimen Handling 7Blood Specimen Collection 7Radiation 6Bevacizumab 5Nivolumab 4Cyclophosphamide 4Biopsy 4vorasidenib 3trametinib 3pembrolizumab 3olaparib 3fludarabine 3dabrafenib 3Watchful Waiting 3Surgical Procedures, Operative 3Magnetic Resonance Imaging 3Drug Therapy 3olutasidenib 2lutetium Lu 177 dotatate 2fluorodopa F 18 2fluciclovine F-18 2entrectinib 2contrast agent BR1 2X-Rays 2Restraint, Physical 2Radiosurgery 2Microdialysis 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Recruiting × Glioma × Radiation × Clear all
NCT05099003 2026-05-27

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

National Cancer Institute (NCI)

Phase 1/2 Recruiting
132 enrolled
CNS

Glioma

NCT05030298 2026-04-22

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

Mayo Clinic

Phase 1 Recruiting
28 enrolled
CNS

Glioma

NCT03739411 2026-03-27

Hyperpolarized Imaging in Diagnosing Participants With Glioma

University of California, San Francisco

Phase 1 Recruiting
140 enrolled
CNS

Glioma

NCT06519682 2025-08-29

A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG)

The Hospital for Sick Children

Phase NA Recruiting
20 enrolled
CNS

Glioma

NCT05271240 2024-09-19

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Northwell Health

Phase 3 Recruiting
432 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma

NCT06305910 2024-03-12

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

OX2 Therapeutics

Phase 1 Recruiting
24 enrolled
CNS

Glioma

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