Announcements Trials
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Phase

Phase 2 69Phase 1 41Phase 1/2 26Phase 3 7Phase EARLY_PHASE1 6Phase NA 5Phase 4 1Phase 2/3 1

Status

Recruiting 2Withdrawn 1Terminated 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6

Conditions

Glioblastoma 7Glioma 6Brain Neoplasms 3Neuroblastoma 2Sarcoma 1Rhabdoid Tumor 1Recurrence 1Pyloric Stenosis, Hypertrophic 1Pinealoma 1Optic Nerve Glioma 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neoplasms 1Medulloblastoma 1Gliosarcoma 1Ependymoma 1Diffuse Intrinsic Pontine Glioma 1Desmoplastic Small Round Cell Tumor 1Central Nervous System Neoplasms 1Astrocytoma 1

Interventions

Magnetic Resonance Spectroscopy 7Temozolomide 6Radiotherapy 6fluciclovine F-18 4Topotecan 4fluorodopa F 18 3Biopsy 3niraparib 2abemaciclib 2Standard of Care 2Specimen Handling 2Pemetrexed 2Ketoconazole 2ulixertinib 1temsirolimus 1ribociclib 1posaconazole 1poly ICLC 1pitavastatin 1pembrolizumab 1orludodstat 1lorlatinib 1larotrectinib 1infigratinib 1fisetin 1fimepinostat 1evolocumab 1clevudine 1X-Rays 1Watchful Waiting 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Glioma × Temozolomide × Clear all
NCT07025226 2026-01-26

Senolytics

Mayo Clinic

Phase EARLY_PHASE1 Recruiting
10 enrolled
CNS

Glioma

NCT06072586 2025-11-20

A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions

St. Joseph's Hospital and Medical Center, Phoenix

Phase EARLY_PHASE1 Recruiting
82 enrolled
CNS

Glioblastoma, Glioma

NCT05634707 2025-09-22

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

Duke University

Phase EARLY_PHASE1 Active not recruiting
10 enrolled
CNS

Brain Neoplasms, Glioma, Recurrence

NCT02970448 2025-06-19

Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

Case Comprehensive Cancer Center

Phase EARLY_PHASE1 Completed
13 enrolled
CNS

Brain Neoplasms, Glioma

NCT02507232 2020-07-28

Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas

Saint John's Cancer Institute

Phase EARLY_PHASE1 Terminated
2 enrolled
CNS

Glioma, Neoplasms

NCT02976441 2017-02-20

Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas

Washington University School of Medicine

Phase EARLY_PHASE1 Withdrawn
CNS

Astrocytoma, Ependymoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

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