Announcements Trials
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Phase

Phase 2 2Phase 4 1Phase 3 1Phase 1 1

Status

Completed 2Withdrawn 1Unknown 1Recruiting 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Leukemia, Myeloid, Acute 10Brain Neoplasms 8Myelodysplastic Syndromes 7Neoplasm Metastasis 6Leukemia, Lymphocytic, Chronic, B-Cell 6Glioblastoma 6Recurrence 5Lymphoma 5Glioma 5Sarcoma 4Leukemia 4Head and Neck Neoplasms 4Colorectal Neoplasms 4Astrocytoma 4Ovarian Neoplasms 3Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Breast Neoplasms 3Uveal Melanoma 2Uterine Cervical Neoplasms 2Thyroid Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Neoplasms, Neuroepithelial 2Nasopharyngeal Carcinoma 2Mouth Neoplasms 2Melanoma 2Medulloblastoma 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2

Interventions

Temozolomide 156Bevacizumab 69Radiotherapy 61Magnetic Resonance Spectroscopy 59Irinotecan 31Surgical Procedures, Operative 23Radiation 23Carboplatin 23Specimen Handling 20Carmustine 20Nivolumab 19Biopsy 17Lomustine 15Aminolevulinic Acid 15Radiotherapy, Intensity-Modulated 13Cyclophosphamide 13trametinib 12pembrolizumab 12Radiosurgery 12Erlotinib Hydrochloride 12fluorodopa F 18 11Topotecan 11Everolimus 11Blood Specimen Collection 11X-Rays 10IL13-PE38 10dabrafenib 9Etoposide 9ribociclib 8poly ICLC 8

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Glioma × Valproic Acid × Clear all
NCT03048084 2025-02-04

STING

Leiden University Medical Center

Phase 4 Recruiting
120 enrolled
CNS

Glioma

NCT01817751 2024-07-17

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Virginia Commonwealth University

Phase 2 Completed
47 enrolled 13 charts
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neurologic Manifestations

NCT03243461 2022-06-06

HIT-HGG-2013

University of Göttingen

Phase 3 Unknown
167 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Baylor College of Medicine

Phase 2 Completed
38 enrolled 53 charts
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT01861990 2015-05-22

Valproic Acid in Childhood Progressive Brain Tumors

Medical University of South Carolina

Phase 1 Withdrawn
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive

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