Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Completed 3

Sponsor Class

OTHER 3NIH 2

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 3

Conditions

Melanoma 63Leukemia, Myeloid, Acute 31Leukemia 25Carcinoma, Renal Cell 23Lymphoma 21Kidney Neoplasms 18Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Neoplasm Metastasis 14Lymphoma, Mantle-Cell 13Myelodysplastic Syndromes 12Lymphoma, Non-Hodgkin 12Lymphoma, Follicular 12Leukemia, Lymphocytic, Chronic, B-Cell 12Neuroblastoma 11Ovarian Neoplasms 10Congenital Abnormalities 10Lymphoma, B-Cell, Marginal Zone 9Breast Neoplasms 9Multiple Myeloma 8Hodgkin Disease 8Carcinoma, Non-Small-Cell Lung 8Stomach Neoplasms 7Recurrence 7Lymphoma, Large B-Cell, Diffuse 7Burkitt Lymphoma 7Lymphoma, Large-Cell, Immunoblastic 6Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6Skin Neoplasms 5Pancreatic Neoplasms 5Myeloproliferative Disorders 5

Interventions

Temozolomide 109Magnetic Resonance Spectroscopy 52Bevacizumab 52Radiotherapy 44Irinotecan 27Blood Specimen Collection 19Surgical Procedures, Operative 16Radiation 15Aminolevulinic Acid 15Carboplatin 13fluorodopa F 18 12Nivolumab 12Radiotherapy, Intensity-Modulated 11Carmustine 11Radiosurgery 10Magnetic Resonance Imaging 10pembrolizumab 9Topotecan 9Specimen Handling 9Everolimus 9Erlotinib Hydrochloride 9Biopsy 9poly ICLC 8Surveys and Questionnaires 8Standard of Care 8Etoposide 8Drug Therapy 8Lomustine 7Filgrastim 7Cyclophosphamide 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Glioma × aldesleukin × Clear all
NCT01082926 2015-06-08

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

City of Hope Medical Center

Phase 1 Completed
6 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00002572 2013-05-30

Cytotoxic T Cells and Interleukin-2 in Treating Adult Patients With Recurrent Brain Tumors

University of Colorado, Denver

Phase 1 Completed
10 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00014573 2013-04-08

Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer

Barbara Ann Karmanos Cancer Institute

Phase 2 Completed
CNSSarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

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