Clinical Trials Browser

Glioma

NCT06666712 2026-04-15

TPT CED rHGG

Phase 1 Recruiting

6 enrolled

CNSLymphoid

Brain Neoplasms, Glioma, Lymphoma, Follicular

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Phase 1 Recruiting

24 enrolled

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

Clinical Trials

PuMP

TPT CED rHGG

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

Hyperpolarized Imaging in Diagnosing Participants With Glioma

PNOC020

APIC-RG

FLUVABREX

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

CILENT

PNOC017

IMPACT

INSIGHT MRL

D2C7 for Adult Patients With Recurrent Malignant Glioma

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

CUE-102 in Recurrent Glioblastoma

rQNestin

Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Feasibility of Individualized Therapy for Recurrent Glioblastoma

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

CARv3-TEAM-E T Cells in Glioblastoma

ACTION

FUS Etoposide for DMG

Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

ENHANCING

GABRIEL

Concurrent Azeliragon With Craniospinal Irradiation

A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma

GLIOSPECT

Peds CHAMP1ON

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

SONOKID

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

A Study of 177Lu-PSMA-617 in People With Gliomas

ETAPA I

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

ASP8374 + Cemiplimab in Recurrent Glioma

Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma