NCT04762602 2026-03-27
A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations
Hutchmed
Phase 1 Terminated
Clinical Trials
46 trialsNCT03334305 2026-01-29
ACTION
University of Florida
Phase 1 Terminated
NCT06193174 2026-01-22
Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)
University of Alabama at Birmingham
Phase 1 Terminated
NCT05429502 2025-10-10
Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors
Novartis
Phase 1 Terminated
NCT06270082 2025-09-19
Study of IK-595 in RAS- or RAF-altered Advanced Tumors
Ikena Oncology
Phase 1 Terminated
NCT01324635 2025-05-02
Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors
Thomas Jefferson University
Phase 1 Terminated
NCT03416530 2025-02-14
ONC201 in Pediatric H3 K27M Gliomas
Jazz Pharmaceuticals
Phase 1 Terminated
NCT04404569 2024-12-20
ETERNITI
Bexion Pharmaceuticals, Inc.
Phase 1 Terminated
NCT04771897 2024-12-20
KONQUER
Bexion Pharmaceuticals, Inc.
Phase 1 Terminated
NCT03296696 2024-10-29
Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma
Amgen
Phase 1 Terminated
NCT01246869 2024-10-01
Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water
University of Utah
Phase 1 Terminated
NCT02924038 2024-06-14
A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)
University of California, San Francisco
Phase 1 Terminated
NCT02833701 2023-10-24
Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma
University of Nebraska
Phase 1 Terminated
NCT02659800 2023-10-06
Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Terminated
NCT03971734 2023-10-06
Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Terminated
NCT04608812 2023-08-18
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection
OncoSynergy, Inc.
Phase 1 Terminated
NCT04541225 2023-07-14
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors
Nuvation Bio Inc.
Phase 1 Terminated
NCT03332355 2023-05-24
Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2
Vanquish Oncology, Inc.
Phase 1 Terminated
NCT01700569 2023-02-21
FOLAGLI
Institut Cancerologie de l'Ouest
Phase 1 Terminated
NCT02433392 2021-04-21
Study of Intraparenchymal Therapy as Adjunct Therapy in Patients With Recurrent, Resectable Glioblastoma Multiforme.
Boston Scientific Corporation
Phase 1 Terminated
NCT03283631 2021-04-05
INTERCEPT
Duke University
Phase 1 Terminated
NCT02029690 2020-09-25
TRAP
Polaris Group
Phase 1 Terminated
NCT04327011 2020-03-30
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
Tocagen Inc.
Phase 1 Terminated
NCT02764151 2020-01-27
First in Patient Study for PF-06840003 in Malignant Gliomas
Pfizer
Phase 1 Terminated
NCT00108056 2019-12-05
Enzastaurin to Treat Recurrent Brain Tumor
National Institutes of Health Clinical Center (CC)
Phase 1 Terminated
NCT00671801 2018-11-13
Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase I
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT00038389 2018-11-01
Study of Vioxx and Radiation Therapy for Brainstem Glioma
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT02176720 2018-08-17
Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma
The Methodist Hospital Research Institute
Phase 1 Terminated
NCT01103375 2018-08-01
Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma
Wake Forest University Health Sciences
Phase 1 Terminated
NCT00880061 2018-07-05
An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma
National Institutes of Health Clinical Center (CC)
Phase 1 Terminated
NCT02305056 2018-05-09
CARBONOMIC
University Hospital, Grenoble
Phase 1 Terminated
NCT00003926 2017-11-29
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
Masonic Cancer Center, University of Minnesota
Phase 1 Terminated
NCT00253721 2017-04-21
Melphalan With BBBD in Treating Patients With Brain Malignancies
OHSU Knight Cancer Institute
Phase 1 Terminated
NCT01902771 2017-03-10
Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
University of Miami
Phase 1 Terminated
NCT01148966 2017-02-15
Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors
University of Washington
Phase 1 Terminated
NCT01502605 2017-01-05
Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Terminated
NCT02371031 2016-11-30
FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas
Washington University School of Medicine
Phase 1 Terminated
NCT01989052 2016-08-04
Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma
Duke University
Phase 1 Terminated
NCT01954030 2016-02-19
Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure
Duke University
Phase 1 Terminated
NCT02240758 2015-11-26
GLIOFOCAL
Hospices Civils de Lyon
Phase 1 Terminated
NCT01378481 2014-12-23
High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma
National Cancer Institute (NCI)
Phase 1 Terminated
NCT01269411 2013-02-07
RO4929097 in Treating Patients With Recurrent Invasive Gliomas
National Cancer Institute (NCI)
Phase 1 Terminated
NCT00110032 2013-01-16
Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors
National Cancer Institute (NCI)
Phase 1 Terminated
NCT00516282 2011-08-26
VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma
Northwestern University
Phase 1 Terminated
NCT00826930 2010-08-12
Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma
Diffusion Pharmaceuticals Inc
Phase 1 Terminated
NCT00003567 2010-06-11
Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Case Comprehensive Cancer Center
Phase 1 Terminated