Announcements Trials
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Phase

Phase NA 1Phase 3 1Phase 1/2 1

Status

Completed 20Active not recruiting 3Unknown 2Recruiting 2Withdrawn 1

Sponsor Class

OTHER 53INDUSTRY 21NIH 17NETWORK 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Breast Neoplasms 19Multiple Myeloma 16Prostatic Neoplasms 14Carcinoma, Non-Small-Cell Lung 12Neoplasms 10Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma 9Leukemia, Myeloid, Acute 7Lung Neoplasms 6Leukemia, Biphenotypic, Acute 6Squamous Cell Carcinoma of Head and Neck 5Neuroblastoma 5Medulloblastoma 5Lymphoma, Mantle-Cell 5Leukemia 5Hodgkin Disease 5Ependymoma 5Colorectal Neoplasms 5Oropharyngeal Neoplasms 4Neoplasm Metastasis 4Myelodysplastic Syndromes 4Leukemia, Myeloid, Chronic-Phase 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Burkitt Lymphoma 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Oligodendroglioma 3Melanoma 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hematologic Neoplasms 3Glioma 3

Interventions

trametinib 1dabrafenib 1Temozolomide 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Hydroxychloroquine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Active not recruiting × NETWORK × Glioma × Clear all
NCT03033992 2026-06-02

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Children's Oncology Group

Phase NA Active not recruiting
80 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioma

NCT04201457 2026-02-03

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Pediatric Brain Tumor Consortium

Phase 1/2 Active not recruiting
57 enrolled
CNS

Glioma

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Eastern Cooperative Oncology Group

Phase 3 Active not recruiting
540 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

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