Clinical Trials Browser

Glioma

NCT06666712 2026-04-15

TPT CED rHGG

Phase 1 Recruiting

6 enrolled

CNSLymphoid

Brain Neoplasms, Glioma, Lymphoma, Follicular

NCT06607692 2026-04-14

LUPARPED

Phase 1/2 Recruiting

25 enrolled

CNSEndocrineNETSarcoma

Adrenal Cortex Neoplasms, Adrenal Gland Neoplasms, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroblastoma, Paraganglioma, Pheochromocytoma, Recurrence, Osteosarcoma, Sarcoma, Synovial, Esthesioneuroblastoma, Olfactory, Neuroendocrine Tumors

Clinical Trials

PuMP

TPT CED rHGG

LUPARPED

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4)

Targeted Pediatric High-Grade Glioma Therapy

Hyperpolarized Imaging in Diagnosing Participants With Glioma

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

NEURO-SUTURE

FIH Clinical Investigation of Graphene Electrodes for Brain Mapping

MRI in High-Grade Glioma Patients Undergoing Chemoradiation

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

SUR-CAN

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Clinical, patHOlogical and Imaging Project of nEuro-oncology (HOPE)

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas

CUE-102 in Recurrent Glioblastoma

SC-Het-GM-CCS

Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma

Methimazole in Patients With Progressive Glioblastoma

Improve TMZ

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

BRAINS

NEMO

Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas

Window of Opportunity Study of DSP-0390 in Gliomas

BRAIN MATRIX

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Development of MRF for Characterization of Brain Tumors After Radiotherapy

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

CSF-IMR

Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

Evaluation of the CONVIVO System

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

CARv3-TEAM-E T Cells in Glioblastoma