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Terminated × Glioma × Clear all

NCT04559685 2026-05-14

Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma

Phase EARLY_PHASE1 Terminated

Glioma

NCT05773326 2026-05-14

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Phase EARLY_PHASE1 Terminated

Glioblastoma, Glioma

NCT03334305 2026-04-23

ACTION

Phase 1 Terminated

18 enrolled 11 charts

Glioma

NCT05189366 2026-04-14

SOPHNEURO

Phase NA Terminated

13 enrolled 8 charts

Communication Disorders, Glioma

NCT04762602 2026-03-27

A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations

Phase 1 Terminated

42 enrolled 26 charts

CNSGastrointestinal

Glioma, Cholangiocarcinoma

NCT01743950 2026-03-25

A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Phase 2 Terminated

49 enrolled 19 charts

Glioblastoma, Glioma

NCT03796273 2026-03-20

Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

Phase EARLY_PHASE1 Terminated

Astrocytoma, Glioma, Oligodendroglioma

NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2 Terminated

19 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT06193174 2026-01-22

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

Phase 1 Terminated

Brain Neoplasms, Glioma, Recurrence

NCT05267106 2025-12-30

FIGHT-209

Phase 2 Terminated

83 enrolled 18 charts

Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT04209790 2025-11-10

NeoGlio

Phase 2 Terminated

2 enrolled 7 charts

Glioblastoma, Glioma

NCT04424966 2025-10-24

Infigratinib in Recurrent High-Grade Glioma Patients

Phase EARLY_PHASE1 Terminated

7 enrolled 18 charts

Glioblastoma, Glioma

NCT03868943 2025-10-21

JAZZ

Phase 2 Terminated

2 enrolled 5 charts

Glioblastoma, Glioma

NCT00897286 2025-10-20

Study of Stored Tumor Samples in Young Patients With Brain Tumors

Familial ependymoma, Glioma, Medulloblastoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor

NCT05429502 2025-10-10

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Phase 1 Terminated

Glioma, Medulloblastoma, Neuroblastoma, Recurrence, Rhabdomyosarcoma

NCT06270082 2025-09-19

Study of IK-595 in RAS- or RAF-altered Advanced Tumors

Phase 1 Terminated

CNSDermatologicGastrointestinalHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Pancreatic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms

NCT03149575 2025-09-04

STAR-3

Phase 3 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT03330197 2025-08-12

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Phase 1/2 Terminated

6 enrolled 14 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Phase 2 Terminated

90 enrolled 24 charts

Glioblastoma, Glioma

NCT06038760 2025-07-30

PEAR-GLIO

Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Neoplasms, Oligodendroglioma

NCT03295396 2025-07-28

ONC201 in Adults With Recurrent H3 K27M-mutant Glioma

Phase 2 Terminated

73 enrolled 13 charts 1 FDA

Glioma

NCT05297864 2025-05-23

OU-SCC-PI-4G

Phase 2 Terminated

15 enrolled 13 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01324635 2025-05-02

Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors

Phase 1 Terminated

Brain Neoplasms, Glioma, Meningioma

NCT03095248 2025-04-22

SEL-TH-1601

Phase 2 Terminated

10 enrolled 9 charts

Ependymoma, Glioma, Meningioma, Neuroma, Acoustic, Neurofibromatosis 2

NCT03690869 2025-04-08

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Phase 1/2 Terminated

57 enrolled 31 charts

Diffuse Intrinsic Pontine Glioma, Glioma, Recurrence, Central Nervous System Neoplasms

NCT05737212 2025-02-21

Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas

Phase 1/2 Terminated

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT03416530 2025-02-14

ONC201 in Pediatric H3 K27M Gliomas

Phase 1 Terminated

134 enrolled 1 FDA

Diffuse Intrinsic Pontine Glioma, Glioma

NCT04552756 2025-01-15

SURF-ROGG

Phase NA Terminated

Glioma, Seizures

NCT05500508 2024-12-24

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Phase 1/2 Terminated

BreastCNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckOther solid neoplasmThoracic

Thyroid Cancer, Papillary, Diffuse Intrinsic Pontine Glioma, Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioma, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT04404569 2024-12-20

ETERNITI

Phase 1 Terminated

Glioblastoma, Glioma, Neoplasms

NCT04771897 2024-12-20

KONQUER

Phase 1 Terminated

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioma

NCT04128774 2024-11-26

GBMdexaB

Glioblastoma, Glioma

NCT02372409 2024-11-01

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Phase 2 Terminated

6 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

NCT03973918 2024-10-31

BRAF

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT03296696 2024-10-29

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Phase 1 Terminated

30 enrolled 29 charts

Glioblastoma, Glioma

NCT01246869 2024-10-01

Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water

Phase 1 Terminated

Brain Neoplasms, Glioblastoma, Glioma, Meningioma, Neoplasms

NCT02924038 2024-06-14

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

Phase 1 Terminated

14 enrolled 10 charts

Astrocytoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT02386241 2024-04-19

Identification of Genomic Changes in Families Having Multiple Members With Tumors

Brain Neoplasms, Glioma

NCT04556929 2024-03-22

EDGE

Phase NA Terminated

Glioma

NCT05394558 2023-12-26

AsiDNA

Phase 1/2 Terminated

Glioma

NCT02833701 2023-10-24

Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma

Phase 1 Terminated

Glioblastoma, Glioma

NCT02659800 2023-10-06

Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas

Phase 1 Terminated

Glioma, Lymphopenia

NCT03593993 2023-10-06

A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas

Astrocytoma, Glioblastoma, Glioma

NCT03971734 2023-10-06

Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

Phase 1 Terminated

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT02095353 2023-08-23

Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients

Brain Neoplasms, Glioma, Neoplasm Metastasis, Central Nervous System Neoplasms

NCT04608812 2023-08-18

Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection

Phase 1 Terminated

Astrocytoma, Glioblastoma, Glioma

NCT04541225 2023-07-14

Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors

Phase 1 Terminated

BreastCNSGenitourinary

Breast Neoplasms, Glioblastoma, Glioma, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT04650204 2023-06-22

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Phase 4 Terminated

4 enrolled 9 charts

Drug Resistant Epilepsy, Epilepsy, Glioma

NCT03927274 2023-05-25

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Glioma

NCT05875935 2023-05-25

ECoG

Phase NA Terminated

Glioma