Announcements Trials
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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Neoplasms 4Vomiting 3Nausea 2Anorexia 2Weight Loss 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Opioid-Related Disorders 1Muscular Atrophy 1Multiple Myeloma 1Lung Neoplasms 1Hematologic Neoplasms 1Gynecologic Cancer 1Gliosarcoma 1Glioblastoma 1Esophageal Neoplasms 1Colorectal Neoplasms 1Child Nutrition Disorders 1Carcinoma, Non-Small-Cell Lung 1Cachexia 1Breast Neoplasms 1

Interventions

Temozolomide 15Radiotherapy 10Radiation 8Magnetic Resonance Spectroscopy 7pembrolizumab 5Specimen Handling 5Ipilimumab 3atezolizumab 2Photons 2Nivolumab 2Biopsy 2veliparib 1selinexor 1sargramostim 1plerixafor 1peposertib 1pazopanib 1navtemadlin; 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid 1montanide ISA 51 1liposomal doxorubicin 1gosha-jinki-gan 1fluorodopa F 18 1ferric pyrophosphate 1efineptakin alfa 1cemiplimab 1cabozantinib 1balstilimab 1abexinostat 1X-Rays 1Vorinostat 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Gliosarcoma × Olanzapine × 1 year × Clear all
NCT04216329 2026-01-23

Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1 Active not recruiting
11 enrolled 19 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

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