Announcements Trials
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Phase

Phase 3 1Phase 2/3 1Phase 2 1Phase 1 1

Status

Active not recruiting 2Recruiting 1Completed 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Sarcoma 4CNS 3

Conditions

Prostatic Neoplasms 12Lung Neoplasms 11Carcinoma, Non-Small-Cell Lung 11Oropharyngeal Neoplasms 10Glioblastoma 10Breast Neoplasms 9Urinary Bladder Neoplasms 7Glioma 6Squamous Cell Carcinoma of Head and Neck 5Sarcoma 5Neoplasm Metastasis 5Mouth Neoplasms 5Esophageal Neoplasms 5Carcinoma 5Burkitt Lymphoma 5Astrocytoma 5Uterine Cervical Neoplasms 4Rhabdomyosarcoma 4Pancreatic Neoplasms 4Laryngeal Neoplasms 4Histiocytoma, Malignant Fibrous 4Gliosarcoma 4Carcinoma, Hepatocellular 4Adenocarcinoma of Lung 4Triple Negative Breast Neoplasms 3Stomach Neoplasms 3Sarcoma, Synovial 3Rhabdomyosarcoma, Embryonal 3Rectal Neoplasms 3Neoplasms 3

Interventions

Temozolomide 10Radiotherapy 5Radiation 4Magnetic Resonance Spectroscopy 4Ipilimumab 3pembrolizumab 2Specimen Handling 2Photons 2Nivolumab 2veliparib 1sargramostim 1peposertib 1montanide ISA 51 1liposomal doxorubicin 1cemiplimab 1balstilimab 1abexinostat 1X-Rays 1Vorinostat 1Utrogestan 1Surgical Procedures, Operative 1Sonication 1Progestins 1Progesterone 1Perfusion Magnetic Resonance Imaging 1Mycophenolic Acid 1Lomustine 1Irinotecan 1Drug Therapy 1Contrast Media 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Gliosarcoma × Radiation × 90 days × Clear all
NCT04555577 2026-05-20

Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma

M.D. Anderson Cancer Center

Phase 1 Recruiting
29 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT05095376 2026-05-19

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

NRG Oncology

Phase 3 Active not recruiting
265 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT04396860 2026-04-22

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

National Cancer Institute (NCI)

Phase 2/3 Completed
159 enrolled 17 charts
Sarcoma

Gliosarcoma

NCT03197506 2026-03-25

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Mayo Clinic

Phase 2 Active not recruiting
52 enrolled 19 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

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