Announcements Trials
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Phase

Phase 1 11Phase 2 5Phase 2/3 2Phase NA 1Phase EARLY_PHASE1 1Phase 3 1Phase 1/2 1

Status

Recruiting 2Active not recruiting 2Completed 1

Sponsor Class

OTHER 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Sarcoma 5CNS 5

Conditions

Carcinoma, Non-Small-Cell Lung 226Breast Neoplasms 223Prostatic Neoplasms 163Multiple Myeloma 147Neoplasms 130Leukemia, Myeloid, Acute 117Colorectal Neoplasms 117Lung Neoplasms 112Neoplasm Metastasis 95Squamous Cell Carcinoma of Head and Neck 90Carcinoma, Hepatocellular 88Melanoma 83Lymphoma 81Triple Negative Breast Neoplasms 74Pancreatic Neoplasms 73Ovarian Neoplasms 72Sarcoma 66Lymphoma, Large B-Cell, Diffuse 63Carcinoma, Renal Cell 63Brain Neoplasms 62Recurrence 58Head and Neck Neoplasms 57Stomach Neoplasms 54Precursor Cell Lymphoblastic Leukemia-Lymphoma 54Leukemia, Lymphocytic, Chronic, B-Cell 53Urinary Bladder Neoplasms 52Hematologic Neoplasms 52Lymphoma, Non-Hodgkin 51Small Cell Lung Carcinoma 50Endometrial Neoplasms 47

Interventions

pembrolizumab 2Temozolomide 2sargramostim 1montanide ISA 51 1liposomal doxorubicin 1balstilimab 1Surgical Procedures, Operative 1Specimen Handling 1Radiotherapy 1Radiation 1Nivolumab 1Magnetic Resonance Spectroscopy 1Ipilimumab 1Colony-Stimulating Factors 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 2 × Gliosarcoma × 90 days × Clear all
NCT05864534 2026-05-13

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Northwestern University

Phase 2 Recruiting
25 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT04817254 2026-04-17

Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
47 enrolled
CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Mayo Clinic

Phase 2 Recruiting
36 enrolled
CNSSarcoma

Astrocytoma, Glioblastoma, Gliosarcoma

NCT02455557 2026-03-30

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Roswell Park Cancer Institute

Phase 2 Active not recruiting
66 enrolled 11 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT03197506 2026-03-25

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Mayo Clinic

Phase 2 Active not recruiting
52 enrolled 19 charts
CNSSarcoma

Glioblastoma, Gliosarcoma

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