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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Meningioma 2Typical Teratoid Rhabdoid Tumor 1Pinealoma 1Paraganglioma 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neuroectodermal Tumors 1Neoplasms, Neuroepithelial 1Medulloblastoma 1Gliosarcoma 1Glioma 1Glioblastoma 1Ependymoma 1Choroid Plexus Neoplasms 1Central Nervous System Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 7Bevacizumab 4sargramostim 2rindopepimut 2Radiotherapy 2Radiation 2Oncolytic Virotherapy 2Granulocyte-Macrophage Colony-Stimulating Factor 2Cyclophosphamide 21-methyltryptophan 2ridaforolimus 1prinomastat 1pembrolizumab 1pamiparib 1marizomib 1interferon gamma-1b 1enzastaurin 1depatuxizumab mafodotin 1capmatinib 1Sucrose 1Spermine Synthase 1Radiosurgery 1Procarbazine 1ONC206 1NVP-BKM120 1Leflunomide 1Interferon-gamma 1Interferon-beta 1Immunotherapy 1Fentanyl 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
INDUSTRY × Gliosarcoma × ONC206 × Clear all
NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Jazz Pharmaceuticals

Phase 1 Recruiting
102 enrolled
CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

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