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Phase

Phase 1 3Phase 2 2Phase EARLY_PHASE1 1Phase 3 1Phase 1/2 1

Status

Completed 2Terminated 1

Sponsor Class

NIH 2OTHER 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 3

Conditions

Brain Neoplasms 21Carcinoma, Non-Small-Cell Lung 16Pancreatic Neoplasms 11Neoplasm Metastasis 11Prostatic Neoplasms 9Melanoma 9Lung Neoplasms 8Glioblastoma 8Breast Neoplasms 8Carcinoma, Hepatocellular 7Squamous Cell Carcinoma of Head and Neck 6Glioma 6Carcinoma, Renal Cell 6Neoplasms 5Colorectal Neoplasms 5Head and Neck Neoplasms 4Uveal Melanoma 3Oligodendroglioma 3Liver Neoplasms 3Gliosarcoma 3Astrocytoma 3Adenocarcinoma 3Vulvar Neoplasms 2Vaginal Neoplasms 2Uterine Cervical Neoplasms 2Urinary Bladder Neoplasms 2Small Cell Lung Carcinoma 2Oropharyngeal Neoplasms 2Mouth Neoplasms 2Laryngeal Neoplasms 2

Interventions

Temozolomide 48Radiotherapy 26Radiation 13Chemotherapy, Adjuvant 9O(6)-benzylguanine 8Irinotecan 8Carmustine 8Surgical Procedures, Operative 7Magnetic Resonance Spectroscopy 6Erlotinib Hydrochloride 6motexafin gadolinium 5Radiotherapy, Intensity-Modulated 5Imatinib Mesylate 5sargramostim 4Radiotherapy, Conformal 4Hydroxyurea 4Gene Expression Profiling 4lonafarnib 3Radiosurgery 3Immunohistochemistry 3Genetic Therapy 3Filgrastim 3Drug Therapy 32,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 3vandetanib 2tipifarnib 2temsirolimus 2cediranib 2aldesleukin 2Vorinostat 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Gliosarcoma × Radiosurgery × Clear all
NCT02186509 2025-04-30

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Thomas Jefferson University

Phase 1 Completed
17 enrolled 11 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01378481 2014-12-23

High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

National Cancer Institute (NCI)

Phase 1 Terminated
30 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00004262 2013-06-04

Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme

National Cancer Institute (NCI)

Phase 1 Completed
12 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

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