Announcements Trials
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Phase

Phase 1/2 5Phase 1 4Phase 2 3Phase 3 1

Status

Completed 3Terminated 1

Sponsor Class

NIH 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Sarcoma 4CNS 4

Conditions

Glioblastoma 6Gliosarcoma 4Carcinoma, Non-Small-Cell Lung 4Pancreatic Neoplasms 3Uterine Cervical Neoplasms 2Rectal Neoplasms 2Pinealoma 2Medulloblastoma 2Glioma 2Adenocarcinoma of Lung 2Urinary Bladder Neoplasms 1Unspecified Adult Solid Tumor, Protocol Specific 1Tongue Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Salivary Gland Neoplasms 1Pancreatic Adenocarcinoma 1Ovarian Neoplasms 1Oligodendroglioma 1Neuroma, Acoustic 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Meningioma 1Glioma, Subependymal 1Ganglioneuroblastoma 1Fallopian Tube Neoplasms 1Ependymoma 1Craniopharyngioma 1Colorectal Neoplasms 1Choroid Plexus Neoplasms 1Astrocytoma 1

Interventions

Temozolomide 48Radiotherapy 26Radiation 13Chemotherapy, Adjuvant 9O(6)-benzylguanine 8Irinotecan 8Carmustine 8Surgical Procedures, Operative 7Magnetic Resonance Spectroscopy 6Erlotinib Hydrochloride 6motexafin gadolinium 5Radiotherapy, Intensity-Modulated 5Imatinib Mesylate 5sargramostim 4Radiotherapy, Conformal 4Hydroxyurea 4Gene Expression Profiling 4lonafarnib 3Radiosurgery 3Immunohistochemistry 3Genetic Therapy 3Filgrastim 3Drug Therapy 32,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 3vandetanib 2tipifarnib 2temsirolimus 2cediranib 2aldesleukin 2Vorinostat 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Gliosarcoma × Radiotherapy, Conformal × Clear all
NCT04397679 2025-01-15

Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

Barbara Ann Karmanos Cancer Institute

Phase 1 Terminated
2 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT01119599 2015-09-29

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

National Cancer Institute (NCI)

Phase 1 Completed
22 enrolled
CNSSarcoma

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroma, Acoustic, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00004262 2013-06-04

Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme

National Cancer Institute (NCI)

Phase 1 Completed
12 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

NCT00316849 2013-04-10

Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

National Cancer Institute (NCI)

Phase 1 Completed
56 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

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