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NCT04396860 2026-04-22

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Phase 2/3 Completed

159 enrolled 17 charts

Gliosarcoma

NCT03746080 2025-11-14

Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma

Phase 2 Completed

21 enrolled 12 charts

Glioblastoma, Glioma, Gliosarcoma

NCT03174197 2025-09-24

Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

Glioblastoma, Gliosarcoma

NCT01165632 2025-09-02

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

Phase EARLY_PHASE1 Completed

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma

NCT03137888 2025-08-03

Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma

Phase 2 Completed

30 enrolled 12 charts

Glioblastoma, Gliosarcoma

NCT03452930 2025-06-04

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT01922076 2024-01-31

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Phase 1 Completed

46 enrolled 20 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Gliosarcoma

NCT00028678 2023-06-18

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01269424 2023-03-02

BG & TMZ Therapy of Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Phase 2 Completed

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT01730950 2022-12-29

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Phase 2 Completed

182 enrolled 19 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01062399 2022-06-09

RTOG 0913

Phase 1/2 Completed

279 enrolled 14 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01004874 2022-04-13

Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma

Phase 2 Completed

80 enrolled 11 charts

Glioblastoma, Glioma, Gliosarcoma

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Phase 2 Completed

38 enrolled 53 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT01740258 2021-01-26

BBP

Phase 2 Completed

68 enrolled 11 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00052208 2020-10-30

Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

Glioblastoma, Gliosarcoma

NCT00006386 2020-10-22

Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006388 2020-10-22

Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00402116 2020-08-06

Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients

Phase 1/2 Completed

72 enrolled 19 charts

Glioblastoma, Gliosarcoma

NCT00869401 2020-02-13

Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

217 enrolled 12 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02337426 2019-06-28

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT00262730 2019-06-12

Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM

Phase 2 Completed

97 enrolled 11 charts

Glioblastoma, Gliosarcoma

NCT00441142 2019-03-05

Zactima

Phase 1/2 Completed

119 enrolled 15 charts

Glioblastoma, Gliosarcoma

NCT01977677 2018-10-23

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

Phase 1/2 Completed

30 enrolled 11 charts

Glioblastoma, Glioma, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00006452 2018-06-27

Gadolinium Texaphyrin Plus Radiation Therapy in Treating Patients With Supratentorial Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00770471 2018-06-27

ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01310868 2017-10-05

Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma

Phase 2 Completed

59 enrolled 8 charts

Glioblastoma, Gliosarcoma

NCT00187486 2017-09-05

Safety and Efficacy Study of Tarceva, Temodar, and Radiation Therapy in Patients With Newly Diagnosed Brain Tumors

Phase 2 Completed

66 enrolled 8 charts

Glioblastoma, Gliosarcoma

NCT00003996 2016-12-07

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00027612 2016-12-07

Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00085254 2016-02-25

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

112 enrolled 14 charts

Glioblastoma, Gliosarcoma

NCT00003417 2015-11-17

Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01222221 2015-10-14

Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004146 2015-05-08

Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM

Phase 2 Completed

55 enrolled 10 charts

Glioblastoma, Gliosarcoma

NCT00019058 2015-04-29

Radiation Therapy in Treating Patients With Glioblastoma

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00019071 2015-04-29

Chemotherapy Followed by Radiation Therapy in Treating Patients With Malignant Glioma

Phase 1 Completed

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00049387 2015-04-15

Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT00960492 2014-09-22

Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma

Phase 1 Completed

Astrocytoma, Glioblastoma, Gliosarcoma

NCT00650923 2014-05-30

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00274755 2014-05-20

Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas

Phase 2 Completed

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00597402 2014-05-07

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Phase 2 Completed

125 enrolled 9 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00099125 2014-01-24

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00253487 2014-01-06

Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed Gliomas

Phase NA Completed

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002608 2013-07-10

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Phase 2 Completed

CNSEndocrineGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

Familial ependymoma, Thyroid Cancer, Papillary, Mesothelioma, Malignant, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Medulloblastoma, Oligodendroglioma, Pheochromocytoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Carcinoma, Medullary, Glioma, Subependymal, Gliosarcoma, Optic Nerve Glioma, Thyroid Carcinoma, Anaplastic

NCT00003464 2013-06-20

Temozolomide in Treating Adults With Newly Diagnosed Primary Malignant Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00022256 2013-06-18

Motexafin Gadolinium Plus Radiation Therapy to the Brain in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00045565 2013-04-09

Arsenic Trioxide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT00058097 2013-04-09

Tipifarnib and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Gliosarcoma

NCT00004024 2013-04-05

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00003478 2013-02-20

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors

Phase 1/2 Completed

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma