Clinical Trials Browser

Terminated × NIH × Gliosarcoma × Clear all

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Phase 1/2 Terminated

53 enrolled 22 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT03107780 2025-11-13

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT02133183 2024-04-04

Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT03641326 2022-04-19

Sunitinib in Sarcomas of the Central Nervous System

Phase 2 Terminated

5 enrolled 14 charts

Brain Neoplasms, Gliosarcoma

NCT00035373 2019-11-07

Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols

Astrocytoma, Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00112866 2017-06-14

Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma Multiforme

Phase 2 Terminated

30 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01122901 2017-05-03

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma

Phase 2 Terminated

47 enrolled 9 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00436436 2017-03-28

O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

Phase 2 Terminated

12 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01189240 2015-12-14

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Phase 1/2 Terminated

13 enrolled 13 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01122888 2015-04-28

Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme

Phase 1 Terminated

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01378481 2014-12-23

High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

Phase 1 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01269411 2013-02-07

RO4929097 in Treating Patients With Recurrent Invasive Gliomas

Phase 1 Terminated

Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00005856 2013-01-24

Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Terminated

Glioblastoma, Gliosarcoma

NCT00006773 2013-01-24

Bortezomib in Treating Patients With Recurrent Glioma

Phase 1 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT00075491 2013-01-24

Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma Multiforme

Phase 2 Terminated

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00110032 2013-01-16

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Phase 1 Terminated

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00430079 2013-01-16

Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma

Phase NA Terminated

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma