Announcements Trials
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Phase

Phase 2 3Phase 2/3 1

Status

Completed 2Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 2Lymphoid 1

Conditions

Myelodysplastic Syndromes 5Arthritis, Rheumatoid 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Leukemia, Myeloid, Acute 4Graft vs Host Disease 4Lymphoma 3Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Leukemia, Biphenotypic, Acute 2Hematologic Neoplasms 2Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Myocarditis 1Myasthenia Gravis 1Multiple Myeloma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell 1Lymphoma, Large-Cell, Anaplastic 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myelomonocytic, Acute 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia 1Immunoblastic Lymphadenopathy 1Hodgkin Disease 1Arthritis 1Anemia, Refractory 1

Interventions

Cyclophosphamide 64Tacrolimus 55Methotrexate 46Mycophenolic Acid 39Cyclosporine 37fludarabine phosphate 35Busulfan 35Antilymphocyte Serum 32fludarabine 29Sirolimus 26Melphalan 23Peripheral Blood Stem Cell Transplantation 22Radiotherapy 21Methylprednisolone 21Whole-Body Irradiation 19Filgrastim 17thymoglobulin 14Thiotepa 11Stem Cell Transplantation 10Rituximab 10ruxolitinib 9Granulocyte Colony-Stimulating Factor 9Prednisone 7Hematopoietic Stem Cell Transplantation 7Etoposide 7Cord Blood Stem Cell Transplantation 7Alemtuzumab 7Pentostatin 6Cytarabine 6Transplantation 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Interventional × Graft vs Host Disease × Abatacept × Clear all
NCT01743131 2025-12-11

Abatacept as GVHD Prophylaxis Phase 2

Boston Children's Hospital

Phase 2 Completed
186 enrolled 14 charts 1 FDA

Graft vs Host Disease, Neoplasms

NCT07238712 2025-11-20

APTBCy

St. Petersburg State Pavlov Medical University

Phase 2 Recruiting
60 enrolled
MyeloidOther hematologic neoplasm

Graft vs Host Disease, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT03680092 2025-10-02

Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantation

University of California, San Diego

Phase 2 Completed
43 enrolled 10 charts
Other hematologic neoplasm

Graft vs Host Disease, Neoplasms, Hematologic Neoplasms

NCT06475820 2024-08-23

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Phase 2/3 Active not recruiting
150 enrolled
LymphoidMyeloidOther hematologic neoplasm

Graft vs Host Disease, Lymphoma, Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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