Announcements Trials
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Phase

Phase 2 3Phase 3 1

Status

Completed 4Recruiting 3Not yet recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1

Conditions

Primary Myelofibrosis 16Polycythemia Vera 14Myeloproliferative Disorders 11Leukemia, Myeloid, Acute 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Leukemia 6Myelodysplastic Syndromes 5Hematologic Diseases 5Myelodysplastic-Myeloproliferative Diseases 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Graft vs Host Disease 4Bone Marrow Diseases 4Thrombocythemia, Essential 3Neoplasms 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hodgkin Disease 3Thrombocytosis 2Pancreatic Neoplasms 2Multiple Myeloma 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Chronic-Phase 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Bronchiolitis Obliterans Syndrome 2Breast Neoplasms 2Triple Negative Breast Neoplasms 1Recurrence 1Preleukemia 1Precancerous Conditions 1Neoplasms, Plasma Cell 1Neoplasms by Histologic Type 1

Interventions

Tacrolimus 37Methotrexate 27Cyclophosphamide 27Mycophenolic Acid 21fludarabine phosphate 19Busulfan 19Antilymphocyte Serum 19Cyclosporine 18Sirolimus 16Methylprednisolone 16fludarabine 15Peripheral Blood Stem Cell Transplantation 15Melphalan 14Filgrastim 13Radiotherapy 12Whole-Body Irradiation 8Granulocyte Colony-Stimulating Factor 8thymoglobulin 6Stem Cell Transplantation 6Rituximab 6Prednisone 6Pentostatin 6Hematopoietic Stem Cell Transplantation 5Etoposide 5ruxolitinib 4Thiotepa 4Flow Cytometry 4Cytarabine 4Cyclosporins 4Cord Blood Stem Cell Transplantation 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Graft vs Host Disease × ruxolitinib × Clear all
NCT03774082 2025-12-11

REACH 5

Novartis

Phase 2 Completed
46 enrolled 21 charts
Lymphoid

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease, Lymphoma, Follicular

NCT03112603 2025-08-12

A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

Incyte Corporation

Phase 3 Completed
330 enrolled 32 charts 1 FDA

Bronchiolitis Obliterans Syndrome, Graft vs Host Disease

NCT04669210 2025-07-04

PTCyRuxo

St. Petersburg State Pavlov Medical University

Phase 2 Completed
128 enrolled
LymphoidOther hematologic neoplasm

Graft vs Host Disease, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02953678 2021-11-24

A Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH-1)

Incyte Corporation

Phase 2 Completed
71 enrolled 24 charts 1 FDA

Graft vs Host Disease

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