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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1

Conditions

Carcinoma, Non-Small-Cell Lung 61Neoplasms 35Colorectal Neoplasms 32Neoplasm Metastasis 31Breast Neoplasms 30Prostatic Neoplasms 26Pancreatic Neoplasms 26Ovarian Neoplasms 26Recurrence 25Multiple Myeloma 25Melanoma 23Squamous Cell Carcinoma of Head and Neck 22Precursor Cell Lymphoblastic Leukemia-Lymphoma 18Triple Negative Breast Neoplasms 17Endometrial Neoplasms 17Lymphoma, Large B-Cell, Diffuse 16Lung Neoplasms 16Glioblastoma 16Lymphoma, Non-Hodgkin 15Leukemia, Myeloid, Acute 14Burkitt Lymphoma 14Stomach Neoplasms 13Small Cell Lung Carcinoma 12Colonic Neoplasms 12Carcinoma, Renal Cell 12Uterine Cervical Neoplasms 11Lymphoma 11Glioma 11Gastrointestinal Neoplasms 11Lymphoma, Follicular 10

Interventions

sacituzumab govitecan 1berzosertib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × HRD Cancer × 30 days × Clear all
NCT04826341 2026-05-29

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
35 enrolled
Other solid neoplasmThoracic

HRD Cancer

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