Clinical Trials Browser

Creatine deficiency, X-linked, Telomeric 22q13 Monosomy Syndrome, Chromosome 15q, partial deletion, Fragile X Syndrome, Hamartoma Syndrome, Multiple, Tuberous Sclerosis, Rett Syndrome, Angelman Syndrome

NCT07218575 2025-10-20

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

Phase 2/3 Not yet recruiting

60 enrolled

Autistic Disorder, Hamartoma Syndrome, Multiple

NCT04094675 2025-06-10

Sirolimus for Cowden Syndrome With Colon Polyposis

Phase 2 Completed

5 enrolled

Hamartoma Syndrome, Multiple

NCT02991807 2025-02-17

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

Phase 1/2 Completed

46 enrolled 15 charts

Autistic Disorder, Hamartoma Syndrome, Multiple, Intellectual Disability

NCT06712095 2024-12-05

PILLCAM

Phase NA Recruiting

25 enrolled

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis, Hamartoma Syndrome, Multiple, Li-Fraumeni Syndrome

NCT06080165 2024-07-10

Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

Phase 1/2 Withdrawn

Hamartoma Syndrome, Multiple

NCT00600275 2020-12-17

A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer

Phase 1/2 Completed

57 enrolled

Breast

Breast Neoplasms, Hamartoma Syndrome, Multiple, Hereditary Sensory and Autonomic Neuropathies

NCT00620594 2020-12-09

A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer

Phase 1 Completed

183 enrolled

Breast

Breast Diseases, Breast Neoplasms, Hamartoma Syndrome, Multiple, Neoplasms

NCT03495089 2019-02-27

DECODING

Phase NA Completed

147 enrolled

Diabetes Mellitus, Type 2, Diabetic Neuropathies, Hamartoma Syndrome, Multiple

NCT03630523 2018-08-15

RIPS

Phase NA Unknown

30 enrolled

Hamartoma Syndrome, Multiple

NCT00971789 2015-09-30

Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes

Phase 2 Completed

18 enrolled 7 charts

Hamartoma Syndrome, Multiple

Clinical Trials

Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

Sirolimus for Cowden Syndrome With Colon Polyposis

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

PILLCAM

Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer

A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer

DECODING

RIPS

Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes