Announcements Trials
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Phase

Phase 2 2Phase 3 1

Status

Recruiting 1Not yet recruiting 1Completed 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Head & Neck 3

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 49Burkitt Lymphoma 27Leukemia, Biphenotypic, Acute 15Leukemia, Myeloid, Acute 13Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 10Leukemia 10Myelodysplastic Syndromes 9Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma 6Leukemia, Myeloid, Accelerated Phase 6Blast Crisis 6Lymphoma, Non-Hodgkin 5Lymphoma, Mantle-Cell 5Lymphoma, Large B-Cell, Diffuse 5Graft vs Host Disease 5Osteosarcoma 4Medulloblastoma 4Down Syndrome 4Urinary Bladder Neoplasms 3Recurrence 3Primary Myelofibrosis 3Neoplasm Metastasis 3Myeloproliferative Disorders 3Leukemia, Myelomonocytic, Juvenile 3Hematologic Neoplasms 3Head and Neck Neoplasms 3Blastic Plasmacytoid Dendritic Cell Neoplasm 3Thrombocythemia, Essential 2Rhabdoid Tumor 2Polycythemia Vera 2

Interventions

pembrolizumab 59Cisplatin 45Cetuximab 29Radiotherapy 26Carboplatin 24Docetaxel 17Paclitaxel 16Nivolumab 16Surveys and Questionnaires 15Radiotherapy, Intensity-Modulated 13Fluorouracil 12Drug Therapy 12Blood Specimen Collection 11Standard of Care 8tislelizumab 7cemiplimab 6atezolizumab 6Radiation 6Chemoradiotherapy 6toripalimab 5Cyclophosphamide 5130-nm albumin-bound paclitaxel 5nimotuzumab 4fludarabine 4durvalumab 4dostarlimab 4Surgical Procedures, Operative 4Afatinib 4palbociclib 3niraparib 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Head and Neck Neoplasms × Methotrexate × 1 year × Clear all
NCT06997068 2026-05-11

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

Mayo Clinic

Phase 2 Recruiting
25 enrolled
Head & Neck

Carcinoma, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT07361133 2026-04-16

Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer

National Cancer Institute, Egypt

Phase 2 Not yet recruiting
120 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT01856478 2026-01-12

LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

Boehringer Ingelheim

Phase 3 Completed
340 enrolled 23 charts
Head & Neck

Head and Neck Neoplasms

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