Clinical Trials

Head and Neck Neoplasms

NCT05328024 2026-06-05

IPRICE

Phase NA Not yet recruiting

Head and Neck Neoplasms

NCT06458517 2026-06-05

RADIO-PBM

Phase 2 Not yet recruiting

Head and Neck Neoplasms, Stomatitis

NCT07407582 2026-06-05

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

Phase 1/2 Recruiting

25 enrolled

GenitourinaryHead & Neck

Head and Neck Neoplasms, Neoplasms, Testicular Neoplasms, Hearing Loss

NCT07630168 2026-06-05

TIMED

238 enrolled

Head & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Lung Neoplasms

NCT06627270 2026-06-04

Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms

NCT07625423 2026-06-04

EDS01 HN

Phase 1 Recruiting

9 enrolled

Head and Neck Neoplasms, Nasopharyngeal Neoplasms

NCT05984680 2026-06-03

COPD Care Pathway Among Patients With Cancer

Completed

101 enrolled

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive

NCT06192771 2026-06-03

ESSI-SURG

40 enrolled

Phase 1/2 Not yet recruiting

Deglutition Disorders, Head and Neck Neoplasms, Speech

NCT07552558 2026-06-03

Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

45 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Jaw Neoplasms, Laryngeal Neoplasms, Lip Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Tongue Neoplasms

NCT07622381 2026-06-03

Specialist Nurse-Led Nursing Management for Patients Undergoing Head and Neck Cancer Surgery

80 enrolled

Head and Neck Neoplasms

NCT07622914 2026-06-03

The Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer

59 enrolled

Head and Neck Neoplasms, Sarcopenia

NCT05048459 2026-06-02

Comparing Two Surveillance Approaches for People Who Have Received Treatment for HPV-associated Head and Neck Cancer and Show No Signs of Disease

40 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT03691714 2026-06-01

Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Phase 2 Completed

35 enrolled 13 charts

Phase 2 Active not recruiting

Head and Neck Neoplasms, Neoplasm Metastasis

NCT04858269 2026-06-01

First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients

32 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT06563362 2026-06-01

DeEscO

120 enrolled

Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT07556367 2026-06-01

Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients

43 enrolled

Phase 2 Enrolling by invitation

Head and Neck Neoplasms

NCT07618624 2026-06-01

BRIDGE

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02597738 2026-05-29

A Feasibility Study to Further the Development of Lung Cancer-based Precision Medicine

330 enrolled

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms

NCT05787834 2026-05-29

Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Cancer

BreastHead & NeckThoracic

130 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT06851663 2026-05-29

Trop2-targeted immunoPET Imaging of Solid Tumors

Phase 2/3 Recruiting

400 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Nasopharyngeal Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07431099 2026-05-29

RECOLOR-HN

20 enrolled

Phase NA Not yet recruiting

Head and Neck Neoplasms

NCT07606287 2026-05-29

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

4,000 enrolled

BreastCNSDermatologicGastrointestinalHead & Neck

Breast Neoplasms, Endocrine Gland Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Skin Neoplasms, Soft Tissue Neoplasms, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT06528353 2026-05-26

SCREEN-HPV

Phase NA Not yet recruiting

10,000 enrolled

GastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Head and Neck Neoplasms

NCT06998342 2026-05-26

MOHSAHRTSS

24 enrolled

Phase EARLY_PHASE1 Active not recruiting

Head and Neck Neoplasms

NCT01098955 2026-05-22

Smoking Cessation Treatment for Head & Neck Cancer Patients

51 enrolled

Head and Neck Neoplasms, Neoplasms, Smoking Cessation

NCT02308072 2026-05-22

ORCA-2

Phase 1 Completed

16 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT03336606 2026-05-22

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Phase 1 Completed

13 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT03646461 2026-05-22

Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC

Phase 2 Terminated

5 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04169074 2026-05-22

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

Phase 2 Terminated

7 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT07601737 2026-05-22

Nimotuzumab Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

182 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02253238 2026-05-20

Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients

427 enrolled

Dehydration, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms

NCT03491176 2026-05-20

Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer

Active not recruiting

100 enrolled

Head and Neck Neoplasms

NCT03494322 2026-05-20

EACH

Phase 2 Completed

16 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT07264075 2026-05-20

ILLUMINE

Phase 3 Recruiting

780 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05184790 2026-05-19

LEARN

BreastCNSGastrointestinalGenitourinaryHead & Neck

300 enrolled

Arrhythmias, Cardiac, Brain Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Spinal Neoplasms

NCT05218824 2026-05-19

CHIRP

Completed

32 enrolled

Head and Neck Neoplasms

NCT05743569 2026-05-19

3D Specimen Maps for RT Planning

Active not recruiting

13 enrolled

Phase NA Enrolling by invitation

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07595666 2026-05-19

Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.

1,600 enrolled

CNSEndocrineHead & Neck

Amyotrophic Lateral Sclerosis, Brain Neoplasms, Dementia, Epilepsy, Head and Neck Neoplasms, Movement Disorders, Neuroblastoma, Parathyroid Neoplasms, Parkinson Disease, Pituitary Neoplasms, Lewy Body Disease

NCT07596355 2026-05-19

H&NANCE

Not yet recruiting

283 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Leukoplakia, Neoplasms

NCT06904365 2026-05-18

OvAR-Y

Active not recruiting

10 enrolled

Anus Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Rectal Neoplasms, Sarcoma, Stomach Neoplasms, Uterine Neoplasms

NCT07589049 2026-05-15

GATEWAY

Phase 2 Not yet recruiting

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01235052 2026-05-14

MISORL

Phase NA Completed

16 enrolled

Head and Neck Neoplasms

NCT05278039 2026-05-14

Training Swallowing Initiation During Expiration

Phase NA Completed

88 enrolled

Squamous Cell Carcinoma of Head and Neck, Deglutition Disorders, Head and Neck Neoplasms

NCT07557225 2026-05-14

18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

200 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, von Hippel-Lindau Disease, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma

NCT02841748 2026-05-13

A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay Study

Phase 2 Completed

100 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03632200 2026-05-13

NUTRIMAX

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Head and Neck Neoplasms, Nutrition Disorders

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

Phase 1 Recruiting

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT07583914 2026-05-13

Safety, Tolerability, and Preliminary Antitumor Activity of Non-Cationic Peptide-CD47 siRNA in Advanced Solid Tumors

Phase 1 Not yet recruiting

9 enrolled