Announcements Trials
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Phase

Phase 2 4Phase 1 2

Status

Completed 5Withdrawn 1

Sponsor Class

OTHER 6INDUSTRY 5

Study Type

Interventional 6

Sponsor

Cancer Type

Head & Neck 6

Conditions

Carcinoma, Non-Small-Cell Lung 25Squamous Cell Carcinoma of Head and Neck 10Lung Neoplasms 10Neoplasms 6Neoplasm Metastasis 6Head and Neck Neoplasms 6Esophageal Squamous Cell Carcinoma 5Breast Neoplasms 5Pancreatic Neoplasms 4Carcinoma, Squamous Cell 4Stomach Neoplasms 3Esophageal Neoplasms 3Brain Neoplasms 3Prostatic Neoplasms 2Non-small-cell Lung Cancer With Somatic EGFR Mutations 2NSCLC 2Glioblastoma 2Colorectal Neoplasms 2Adenocarcinoma of Lung 2Urinary Bladder Neoplasms 1Urethral Neoplasms 1Ureteral Neoplasms 1Unilateral HER2 Positive Breast Cancer 1Triple Negative Breast Neoplasms 1Thrombocytosis 1Thoracic Neoplasms 1Squamous Cell Cancers of the Head and Neck 1Solid Tumors 1Small Cell Lung Carcinoma 1Skin Neoplasms 1

Interventions

Cisplatin 141Radiotherapy 115Cetuximab 95Docetaxel 69Radiotherapy, Intensity-Modulated 55Carboplatin 47pembrolizumab 46Surveys and Questionnaires 46Paclitaxel 41Fluorouracil 39Radiation 29Blood Specimen Collection 27Drug Therapy 26Erlotinib Hydrochloride 23Nivolumab 21Surgical Procedures, Operative 17Standard of Care 16Magnetic Resonance Spectroscopy 16Radiosurgery 14Pemetrexed 14Gemcitabine 14Everolimus 13Celecoxib 13durvalumab 12Low-Level Light Therapy 12Immunohistochemistry 12Cyclophosphamide 12Capecitabine 12Amifostine 12Chemoradiotherapy 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
OTHER × Head and Neck Neoplasms × Afatinib × Clear all
NCT06494189 2025-12-29

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

West China Hospital

Phase 1 Completed
9 enrolled
Head & Neck

Head and Neck Neoplasms

NCT06804850 2025-11-19

Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC

West China Hospital

Phase 2 Withdrawn
Head & Neck

Head and Neck Neoplasms

NCT05517330 2025-07-31

neoCHANCE-1

West China Hospital

Phase 2 Completed
23 enrolled
Head & Neck

Head and Neck Neoplasms

NCT05516589 2025-05-22

neoCHANCE-2

West China Hospital

Phase 2 Completed
40 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03695510 2022-04-21

ALPHA

National Taiwan University Hospital

Phase 2 Completed
29 enrolled
Head & Neck

Head and Neck Neoplasms

NCT01721525 2017-10-25

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
10 enrolled
Head & Neck

Head and Neck Neoplasms, Neoplasms, Squamous Cell

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