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Phase

Phase NA 1Phase EARLY_PHASE1 1Phase 1/2 1Phase 1 1

Status

Completed 3Terminated 1

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 4

Conditions

Polycystic Ovary Syndrome 139Breast Neoplasms 31Prostatic Neoplasms 29Insulin Resistance 28Obesity 19Pancreatic Neoplasms 13Neoplasms 12Infertility 12Endometrial Neoplasms 12Carcinoma, Non-Small-Cell Lung 12Colorectal Neoplasms 11Anovulation 9Lung Neoplasms 8Metabolic Syndrome 7Melanoma 7Hyperandrogenism 7Glioblastoma 7Diabetes Mellitus 7Squamous Cell Carcinoma of Head and Neck 6Neoplasm Metastasis 6Rectal Neoplasms 5Adenocarcinoma 5Weight Loss 4Urinary Bladder Neoplasms 4Lymphoma, Large B-Cell, Diffuse 4Head and Neck Neoplasms 4Carcinoma, Ovarian Epithelial 4Adenocarcinoma of Lung 4Uterine Cervical Neoplasms 3Recurrence 3

Interventions

Cisplatin 141Radiotherapy 115Cetuximab 95Docetaxel 69Radiotherapy, Intensity-Modulated 55Carboplatin 47pembrolizumab 46Surveys and Questionnaires 46Paclitaxel 41Fluorouracil 39Radiation 29Blood Specimen Collection 27Drug Therapy 26Erlotinib Hydrochloride 23Nivolumab 21Surgical Procedures, Operative 18Standard of Care 16Magnetic Resonance Spectroscopy 16Radiosurgery 14Pemetrexed 14Gemcitabine 14Everolimus 13Celecoxib 13durvalumab 12Low-Level Light Therapy 12Immunohistochemistry 12Cyclophosphamide 12Capecitabine 12Amifostine 12Chemoradiotherapy 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × Head and Neck Neoplasms × Metformin × Clear all
NCT02949700 2023-06-29

Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

Baylor College of Medicine

Phase 1/2 Completed
26 enrolled 14 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03510390 2021-11-18

HEAD-MET

Insel Gruppe AG, University Hospital Bern

Phase NA Completed
17 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02325401 2020-06-11

Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

University of Cincinnati

Phase 1 Completed
20 enrolled 11 charts
Head & Neck

Head and Neck Neoplasms

NCT02402348 2017-02-08

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

West Virginia University

Phase EARLY_PHASE1 Terminated
3 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

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