Clinical Trials

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04722523 2026-03-30

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

Phase 1 Recruiting

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01612351 2026-03-17

Multimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery

40 enrolled 20 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT04222972 2026-03-05

AcceleRET-Lung

Phase 3 Terminated

223 enrolled 18 charts

Head & NeckThoracic

Adenocarcinoma, Bronchial Diseases, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT07065630 2026-03-04

Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer

Phase 2 Recruiting

38 enrolled

Head and Neck Neoplasms

NCT06998069 2025-12-30

Head and Neck Cancer Study Project in the Geriatric Population

Phase 3 Recruiting

20 enrolled

Phase 1/2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04198766 2025-12-18

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

296 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Lung Neoplasms, Melanoma, Mouth Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Oropharyngeal Neoplasms, Stomach Neoplasms, Neoplasms, Squamous Cell

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase 2 Active not recruiting

128 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04338399 2025-11-17

BURAN

Phase 3 Completed

487 enrolled

Head and Neck Neoplasms

NCT05758389 2025-09-05

Tislelizumab Combined APF Chemotherapy in the Treatment of Locally Advanced Head and Neck Tumors

Phase 2 Recruiting

29 enrolled

Head and Neck Neoplasms

NCT04282109 2025-06-26

NIVOTAX

141 enrolled 40 charts

Phase 1 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

39 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT06494943 2025-02-25

Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCC

Phase 1/2 Recruiting

27 enrolled

Phase EARLY_PHASE1 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06062602 2023-10-06

PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC

15 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04572100 2023-07-07

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

50 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00089297 2023-06-29

Cetuximab, Chemotherapy, and Radiation Therapy for Operable Stage III or IV Head and Neck Cancer

74 enrolled 8 charts

Head and Neck Neoplasms

NCT01084083 2023-06-28

Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer

Head & NeckOther neoplasm

90 enrolled 7 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Precancerous Conditions, Tongue Neoplasms, Papillomavirus Infections

NCT00003592 2023-06-22

Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer

Phase 3 Completed

230 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00002922 2023-06-18

Paclitaxel in Treating Patients With Advanced Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00002632 2023-06-15

Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer

32 enrolled

Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT00003206 2023-06-15

Carboplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer

Head and Neck Neoplasms, Nasopharyngeal Neoplasms

NCT00014118 2023-06-15

Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00997906 2022-09-29

Cisplatin and RT With or Without Gemcitabine, Carboplatin, and Paclitaxel in Treating Patients With Locally Advanced NPC

Phase 2/3 Unknown

172 enrolled

Head and Neck Neoplasms

NCT00971867 2022-04-08

Rollover Study of Weekly Paclitaxel (BMS-181339) in Patients With Head and Neck Cancer

11 enrolled 16 charts

Head and Neck Neoplasms

NCT00566540 2021-11-26

Ph 2 Intensification Regimen for Previously Untreated, Resectable, Advanced Squamous Cell Cancer

11 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01716195 2021-02-26

Induction Chemotherapy Followed by Chemoradiotherapy for Head and Neck Cancer

18 enrolled 10 charts

Head and Neck Neoplasms

NCT03887442 2021-01-07

EXTAX

17 enrolled 8 charts

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT02051751 2020-12-08

A Study to Evaluate the Potential Benefit of the Addition of BYL719 to Paclitaxel in the Treatment of Breast Cancer and Head-and-neck Cancer

19 enrolled

BreastHead & Neck

Breast Neoplasms, Head and Neck Neoplasms, Neoplasms

NCT02124707 2020-08-12

Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN

14 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT01133678 2020-05-08

Study in Locally Advanced Squamous Cell Carcinoma of Head and Neck

50 enrolled 9 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00343083 2019-08-19

Evaluation of Cetuximab (ERBITUX) and Concurrent Carboplatin, Paclitaxel & Radiotherapy in the Management of Patients With Advanced Locoregional Squamous Cell Carcinomas of the Head and Neck (GCC 0442)

43 enrolled 11 charts

Head and Neck Neoplasms

NCT01264328 2019-04-16

VECTITAX

40 enrolled

Head and Neck Neoplasms

NCT01721525 2017-10-25

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

10 enrolled

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT01911598 2017-07-06

A Study of MEHD7945A in Combination With Cisplatin and 5-Fluorouracil (5-FU) or Paclitaxel and Carboplatin in Participants With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M SCCHN)

24 enrolled

Head and Neck Neoplasms

NCT00270790 2017-02-01

EVALUATION OF AMIFOSTINE FOR MUCOSAL AND HEMOPOETIC PROTECTION AND CARBOPLATIN, TAXOL, RADIOTHERAPY IN THE MANAGEMENT OF PATIENTS WITH HEAD AND NECK CANCER.(GCC 0202)

21 enrolled 6 charts

Head and Neck Neoplasms

NCT00095927 2017-01-04

Randomized Amifostine For SCCHN

58 enrolled

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia, Mucositis

NCT00003582 2016-12-15

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

Phase 1/2 Completed

36 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Unknown Primary

NCT00580983 2016-09-07

Optimized Intensity Modulated Irradiation for Head and Neck Cancer

Phase NA Completed

90 enrolled 11 charts

Head and Neck Neoplasms

NCT01333085 2016-02-10

CAPRA

Phase 1/2 Completed

49 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT02630264 2015-12-15

E10A for the Treatment of Squamous Cell Carcinoma of the Head and Neck

Phase 3 Unknown

540 enrolled

Head and Neck Neoplasms

NCT00005087 2015-11-17

Paclitaxel, Cisplatin, and Filgrastim Combined With Radiation Therapy in Treating Patients With Locally Recurrent Head and Neck Cancer

105 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00011999 2015-11-17

Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer

70 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00176241 2015-06-08

Phase I Trial of Biweekly Gemcitabine & Paclitaxel & Low-Dose Radiation for Metastatic or Recurrent Head & Neck Cancer

Phase 1 Terminated

7 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT01333852 2015-01-27

METTAX

45 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02013453 2014-12-02

A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer

Phase 2 Withdrawn