Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 3 1

Status

Recruiting 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Head & Neck 3

Conditions

Breast Neoplasms 8Fibrosis 4Head and Neck Neoplasms 3Colorectal Neoplasms 3Mucositis 2Lymphedema 2Erectile Dysfunction 2Sarcoidosis, Pulmonary 1Prostatic Neoplasms 1Primary Ovarian Insufficiency 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycystic Ovary Syndrome 1Peripheral Nervous System Diseases 1Pentoxifylline, Cisplatin, Nephrotoxixcity 1Pancreatitis, Alcoholic 1Pancreatitis 1Pain 1Osteoradionecrosis 1Non-small Cell Lung Cancers 1Neuritis 1Neoplasms 1Long-term Adverse Effects of Radiotherapy for Pelvic Cancer 1Hodgkin Disease 1HIV Infections 1Gliosarcoma 1Glioblastoma 1Colonic Neoplasms 1Central Nervous System Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Capsular Contractures 1

Interventions

Cisplatin 252Radiotherapy 176Cetuximab 144pembrolizumab 120Docetaxel 96Fluorouracil 92Carboplatin 80Paclitaxel 77Radiotherapy, Intensity-Modulated 69Nivolumab 37Radiation 30Drug Therapy 30Erlotinib Hydrochloride 26Gemcitabine 25Gefitinib 21Cyclophosphamide 21Surveys and Questionnaires 20Surgical Procedures, Operative 19Standard of Care 19Pemetrexed 19durvalumab 18Magnetic Resonance Spectroscopy 17Capecitabine 17Radiosurgery 16Celecoxib 16atezolizumab 15Filgrastim 15Amifostine 15Low-Level Light Therapy 14Everolimus 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Head and Neck Neoplasms × Pentoxifylline × Clear all
NCT06912763 2026-01-26

Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

M.D. Anderson Cancer Center

Phase 2 Recruiting
250 enrolled
Head & Neck

Fibrosis, Head and Neck Neoplasms, Lymphedema

NCT06055257 2025-09-12

Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible

Sunnybrook Health Sciences Centre

Phase 3 Recruiting
24 enrolled
Head & Neck

Head and Neck Neoplasms, Osteoradionecrosis

NCT02397486 2019-11-26

The Impact of Pentoxifylline and Vitamin E on Radiotherapy-induced Toxicity in Head & Neck Cancer Patients

Ain Shams University

Phase 2 Completed
60 enrolled
Head & Neck

Head and Neck Neoplasms

Data powered by HemOnc (CC BY 4.0) Colophon âš¡