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Phase EARLY_PHASE1 1

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OTHER 1

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Cancer Type

Head & Neck 1

Conditions

Recurrence 1Leukemia, Lymphocytic, Chronic, B-Cell 1Head and Neck Neoplasms 1Carcinoma, Squamous Cell 1

Interventions

Cisplatin 141Radiotherapy 115Cetuximab 95Docetaxel 69Radiotherapy, Intensity-Modulated 55Carboplatin 47pembrolizumab 46Surveys and Questionnaires 46Paclitaxel 41Fluorouracil 39Radiation 29Blood Specimen Collection 27Drug Therapy 26Erlotinib Hydrochloride 23Nivolumab 21Surgical Procedures, Operative 17Standard of Care 16Magnetic Resonance Spectroscopy 16Radiosurgery 14Pemetrexed 14Gemcitabine 14Everolimus 13Celecoxib 13durvalumab 12Low-Level Light Therapy 12Immunohistochemistry 12Cyclophosphamide 12Capecitabine 12Amifostine 12Chemoradiotherapy 11

Date Range

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Head and Neck Neoplasms × Pyrimethamine × Clear all
NCT05678348 2025-08-17

Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell Carcinoma

Washington University School of Medicine

Phase EARLY_PHASE1 Completed
22 enrolled
Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms

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