Clinical Trials Browser

Head and Neck Neoplasms × Radiotherapy × Clear all

NCT02641093 2026-05-04

Phase II Trial of Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell Carcinoma

Phase 2 Active not recruiting

96 enrolled 12 charts

Head and Neck Neoplasms

NCT07445048 2026-04-17

Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07040969 2026-04-07

Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Phase 2 Active not recruiting

Head and Neck Neoplasms

NCT06110195 2026-03-31

Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer

Phase 1 Terminated

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07353671 2026-03-25

Topical Periplaneta Americana-Derived Meilian Fuxin Liquid for Radiation Dermatitis

Phase 2/3 Recruiting

Head and Neck Neoplasms, Radiodermatitis

NCT01647555 2026-03-18

Radiotherapy in Association With Cetuximab in Patients Treated for an Epidermoid Cancer

Head and Neck Neoplasms

NCT06910566 2026-03-18

TABAC STOP ORL

Active not recruiting

Head and Neck Neoplasms, Smoking, Tobacco Use Disorder, Smoking Cessation

NCT01612351 2026-03-17

Multimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery

Phase 2 Completed

40 enrolled 20 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT03875716 2026-03-13

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

Phase NA Recruiting

Head and Neck Neoplasms

NCT04075305 2026-03-05

MOMENTUM

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms

NCT06208826 2026-03-03

A Single-center Phase II Study to Investigate the Immune Maintenance Therapy Pattern in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Achieved MPR After Neoadjuvant Immunotherapy Combined With Chemotherapy

Phase 2 Recruiting

Head and Neck Neoplasms

NCT05962242 2026-02-05

HN001

Phase 2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03040999 2026-02-04

KEYNOTE-412

Phase 3 Completed

804 enrolled 20 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06998069 2025-12-30

Head and Neck Cancer Study Project in the Geriatric Population

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06494189 2025-12-29

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

Phase 1 Completed

Head and Neck Neoplasms

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03224000 2025-12-17

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT02918955 2025-11-20

UPFRONT-NECK

Phase 3 Completed

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Oropharyngeal Neoplasms

NCT06804850 2025-11-19

Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC

Phase 2 Withdrawn

Head and Neck Neoplasms

NCT03383094 2025-10-07

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

Phase 2 Active not recruiting

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Oropharyngeal Neoplasms, Recurrence

NCT00875849 2025-09-30

AACER

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT01326468 2025-09-25

Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer

Phase NA Withdrawn

Head and Neck Neoplasms

NCT07170358 2025-09-12

RIX

Head and Neck Neoplasms, Xerostomia

NCT07129525 2025-08-19

HOPE

Not yet recruiting

GynecologicHead & Neck

Head and Neck Neoplasms, Pelvic Neoplasms, Radiation Injuries

NCT04545957 2025-07-28

JUMP

Phase NA Recruiting

GastrointestinalGenitourinaryHead & Neck

Adenocarcinoma, Head and Neck Neoplasms, Liver Neoplasms, Prostatic Neoplasms

NCT06940180 2025-06-26

Toripalimab With Chemotherapy for Sinus Cancer

Phase 2 Recruiting

Sinonasal undifferentiated carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Paranasal Sinus Neoplasms

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Phase 1 Active not recruiting

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT00405405 2025-05-06

Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer

Phase 1 Completed

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Parotid Neoplasms, Thyroid Neoplasms

NCT01345084 2025-03-28

NICAP

Phase 3 Withdrawn

Carcinoma, Head and Neck Neoplasms

NCT03721757 2025-02-25

NICO

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

Phase 2 Completed

31 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00559156 2025-02-13

Arginine/Omega-3 Fatty Acids/Nucleotides Nutritional Supplement in Treating Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT03715946 2025-01-13

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Phase 2 Completed

40 enrolled 69 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT03343236 2024-12-13

Nutrition and Inflammation in Patients With Head and Neck Cancer

Active not recruiting

Head and Neck Neoplasms, Inflammation, Radiation Injuries

NCT06700863 2024-11-22

RIX

Head and Neck Neoplasms, Xerostomia

NCT03515538 2024-11-04

PREVLAR

Phase 2 Completed

53 enrolled 15 charts

Head & NeckOther

Head and Neck Neoplasms, Mouth Neoplasms, Stomatitis, Mucositis

NCT00868491 2024-10-18

Induction Chemotherapy Followed by Chemoradiation With Cetuximab in Head and Neck Cancer

Phase 2 Completed

Head and Neck Neoplasms

NCT00720304 2024-08-22

Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

43 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06556979 2024-08-16

RT-CASinHNC

Ischemic Stroke, Ischemic Attack, Transient, Head and Neck Neoplasms, Carotid Stenosis

NCT06428994 2024-05-24

Risk for Subsequent Osteoradionecrosis in A Transferred Fibula Flap in Head and Neck Cancer Patients Undergoing Segmental Mandibulectomy: a Cohort Study

Head and Neck Neoplasms, Osteoradionecrosis

NCT05412849 2024-05-23

Radiation Field, Dose and Fractionation Related to Mandibular Complications

Head and Neck Neoplasms, Osteoradionecrosis

NCT02435576 2024-04-15

H&NTOX

10,000 enrolled

Head and Neck Neoplasms

NCT01979211 2024-02-29

Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

24 enrolled 11 charts

Head and Neck Neoplasms

NCT00502463 2024-02-07

ASOG-HNO1

Phase NA Completed

Head and Neck Neoplasms

NCT02229656 2023-11-07

Olaparib and Radiotherapy in Head and Neck Cancer

Phase 1 Unknown

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms

NCT04572100 2023-07-07

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Phase 1 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00089297 2023-06-29

Cetuximab, Chemotherapy, and Radiation Therapy for Operable Stage III or IV Head and Neck Cancer

Phase 2 Completed

74 enrolled 8 charts

Head and Neck Neoplasms

NCT00096174 2023-06-29

Phase II Study of Concurrent C225, Cisplatin and Radiation in Stage IV Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

69 enrolled 7 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00014118 2023-06-15

Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04435964 2023-03-24

G-DEFINER

BreastDermatologicHead & NeckThoracic

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Urogenital Neoplasms