Clinical Trials

Head and Neck Neoplasms

NCT05962242 2026-02-05

HN001

Phase 2 Recruiting

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06998069 2025-12-30

Head and Neck Cancer Study Project in the Geriatric Population

Phase 3 Recruiting

20 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06494189 2025-12-29

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

9 enrolled

Head and Neck Neoplasms

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

128 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03224000 2025-12-17

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

90 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT02918955 2025-11-20

UPFRONT-NECK

Phase 3 Completed

65 enrolled

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Oropharyngeal Neoplasms

NCT06804850 2025-11-19

Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC

Phase 2 Withdrawn

Head and Neck Neoplasms

NCT03383094 2025-10-07

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

126 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Oropharyngeal Neoplasms, Recurrence

NCT00875849 2025-09-30

AACER

53 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT01326468 2025-09-25

Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer

Phase NA Withdrawn

Head and Neck Neoplasms

NCT07170358 2025-09-12

RIX

126 enrolled

GastrointestinalGenitourinaryHead & Neck

Head and Neck Neoplasms, Xerostomia

NCT07129525 2025-08-19

HOPE

Not yet recruiting

80 enrolled

GynecologicHead & Neck

Head and Neck Neoplasms, Pelvic Neoplasms, Radiation Injuries

NCT04545957 2025-07-28

JUMP

Phase NA Recruiting

86 enrolled

Adenocarcinoma, Head and Neck Neoplasms, Liver Neoplasms, Prostatic Neoplasms

NCT06940180 2025-06-26

Toripalimab With Chemotherapy for Sinus Cancer

Phase 2 Recruiting

20 enrolled

Sinonasal undifferentiated carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Paranasal Sinus Neoplasms

NCT00405405 2025-05-06

Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer

13 enrolled

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Parotid Neoplasms, Thyroid Neoplasms

NCT03721757 2025-02-25

NICO

21 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

31 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00559156 2025-02-13

Arginine/Omega-3 Fatty Acids/Nucleotides Nutritional Supplement in Treating Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

46 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT03715946 2025-01-13

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

40 enrolled 69 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT03343236 2024-12-13

Nutrition and Inflammation in Patients With Head and Neck Cancer

Active not recruiting

522 enrolled

Head and Neck Neoplasms, Inflammation, Radiation Injuries

NCT06700863 2024-11-22

RIX

200 enrolled

Head and Neck Neoplasms, Xerostomia

NCT00868491 2024-10-18

Induction Chemotherapy Followed by Chemoradiation With Cetuximab in Head and Neck Cancer

30 enrolled

Head and Neck Neoplasms

NCT02641093 2024-08-29

Phase II Trial of Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell Carcinoma

96 enrolled 12 charts

Head and Neck Neoplasms

NCT00720304 2024-08-22

Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck

43 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06556979 2024-08-16

RT-CASinHNC

Completed

907 enrolled

Ischemic Stroke, Ischemic Attack, Transient, Head and Neck Neoplasms, Carotid Stenosis

NCT06428994 2024-05-24

Risk for Subsequent Osteoradionecrosis in A Transferred Fibula Flap in Head and Neck Cancer Patients Undergoing Segmental Mandibulectomy: a Cohort Study

Completed

580 enrolled

Head and Neck Neoplasms, Osteoradionecrosis

NCT05412849 2024-05-23

Radiation Field, Dose and Fractionation Related to Mandibular Complications

120 enrolled

Head and Neck Neoplasms, Osteoradionecrosis

NCT02435576 2024-04-15

H&NTOX

10,000 enrolled

Head and Neck Neoplasms

NCT01979211 2024-02-29

Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck

24 enrolled 11 charts

Head and Neck Neoplasms

NCT02229656 2023-11-07

Olaparib and Radiotherapy in Head and Neck Cancer

Phase 1 Unknown

12 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Neoplasms

NCT04572100 2023-07-07

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

50 enrolled

BreastDermatologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04435964 2023-03-24

G-DEFINER

Completed

247 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Urogenital Neoplasms

NCT04359199 2023-02-10

QUASAR

Unknown

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Deglutition Disorders, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT04782726 2023-01-25

Radiation Therapy Plan Quality Improvement Using Ideal Theoretical Isodose Distribution

Phase NA Completed

21 enrolled

Head and Neck Neoplasms

NCT02158234 2023-01-19

Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck

20 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases

NCT00964977 2022-02-25

Effectiveness of Adjuvant Radiotherapy in Small Oropharyngeal Squamous Cell Cancer and Single Lymph Node Metastasis.

Phase 3 Completed

209 enrolled

Head and Neck Neoplasms, Lymphatic Metastasis, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00003777 2022-01-26

Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer

Phase 2 Terminated

35 enrolled

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00566540 2021-11-26

Ph 2 Intensification Regimen for Previously Untreated, Resectable, Advanced Squamous Cell Cancer

Phase 2 Terminated

11 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00660218 2021-11-08

A Phase I/II Study of Radiation Therapy, Paclitaxel Poliglumex and Cetuximab in Advanced Head and Neck Cancer

Phase 1/2 Completed

53 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT05011500 2021-08-18

MASSC

Phase NA Unknown

24 enrolled