Announcements Trials
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Phase

Phase 1/2 2

Status

Completed 1Active not recruiting 1

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Head and Neck Neoplasms 2Vulvar Neoplasms 1Vaginal Neoplasms 1Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Sarcoma 1Prostatic Neoplasms 1Penile Neoplasms 1Pancreatic Neoplasms 1Oropharyngeal Neoplasms 1Neoplasms, Germ Cell and Embryonal 1Neoplasm Metastasis 1Melanoma 1Colonic Neoplasms 1Castration Resistant Prostate Cancer 1Carcinoma, Renal Cell 1Breast Neoplasms 1Anus Neoplasms 1

Interventions

Radiotherapy 26Cisplatin 17Fluorouracil 13Paclitaxel 10Carboplatin 6Chemotherapy, Adjuvant 5Cetuximab 5Immunohistochemistry 4Docetaxel 4Radiotherapy, Intensity-Modulated 3Immunoenzyme Techniques 3Hydroxyurea 3Gemcitabine 3Gefitinib 3Filgrastim 3Bortezomib 3sargramostim 2bintrafusp alfa protein, human 2aldesleukin 2Tetrahydrouridine 2SS1(dsFv)PE38 2Radiotherapy, Conformal 2Polymerase Chain Reaction 2Oxaliplatin 2Neoadjuvant Therapy 2Methotrexate 2Magnetic Resonance Spectroscopy 2Leucovorin 2Gene Expression Profiling 2Fluorodeoxyglucose F18 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Head and Neck Neoplasms × bintrafusp alfa protein, human × Clear all
NCT04708470 2026-04-06

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
55 enrolled
GastrointestinalGenitourinaryGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT04247282 2025-07-16

Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus Infection

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
21 enrolled 16 charts
Head & Neck

Head and Neck Neoplasms

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