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Phase

Phase 2 3Phase 1/2 1

Status

Completed 34Recruiting 26Terminated 21Active not recruiting 21Unknown 9Withdrawn 7Not yet recruiting 4Suspended 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 4

Conditions

Triple Negative Breast Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Squamous Cell Carcinoma of Head and Neck 5Breast Neoplasms 5Head and Neck Neoplasms 4Carcinoma, Renal Cell 4Turcot syndrome 3Neoplasm Metastasis 3Melanoma 3Colorectal Neoplasms 3Uterine Cervical Neoplasms 2Prostatic Neoplasms 2Lung Neoplasms 2Hodgkin Disease 2Glioblastoma 2Endometrial Neoplasms 2Colonic Neoplasms 2Cholangiocarcinoma 2Carcinoma, Hepatocellular 2Biliary Tract Neoplasms 2Advanced Endometrial Cancer 2Tongue Neoplasms 1To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal Carcinoma 1Thyroid Neoplasms 1Thoracic Neoplasms 1Stomach Neoplasms 1Squamous NSCLC 1Respiratory Tract Neoplasms 1Respiratory Tract Diseases 1Rare Tumour 1

Interventions

pembrolizumab 4Blood Specimen Collection 4Cyclophosphamide 3Cisplatin 3fludarabine 2Tissue Banks 2Surgical Procedures, Operative 2Nivolumab 2Docetaxel 2130-nm albumin-bound paclitaxel 2tislelizumab 1fludarabine phosphate 1cemiplimab 1Therapeutics 1Surgical Flaps 1Standard of Care 1Sodium Chloride 1Radiotherapy, Intensity-Modulated 1Radiotherapy 1Radiation Dose Hypofractionation 1Neoadjuvant Therapy 1Methotrexate 1Magnetic Resonance Spectroscopy 1Magnetic Resonance Imaging 1Low-Level Light Therapy 1Ketamine 1Immune Checkpoint Inhibitors 1Gastroscopy 1Etoposide 1Electric Stimulation 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Not yet recruiting × Head and Neck Neoplasms × pembrolizumab × Clear all
NCT07484139 2026-05-08

NEO COMBAT XL

UNC Lineberger Comprehensive Cancer Center

Phase 2 Not yet recruiting
26 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07552558 2026-04-27

Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Washington University School of Medicine

Phase 1/2 Not yet recruiting
45 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Jaw Neoplasms, Laryngeal Neoplasms, Lip Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Tongue Neoplasms

NCT06894459 2025-04-30

A Prospective, Multicenter, Multicohort Phase II Study: Evaluating the Efficacy and Safety of Preoperative Neoadjuvant Treatment With a PD-1 Inhibitor in Combination With Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma

Beijing Tongren Hospital

Phase 2 Not yet recruiting
180 enrolled
Head & Neck

Head and Neck Neoplasms

NCT06793761 2025-01-27

A Phase II Study to Evaluate the Efficacy and Safety of Salvage Preoperative PD-1 Inhibitor Combined with Chemotherapy Neoadjuvant Therapy in Recurrent and Metastatic LPSCC/HPSCC

Beijing Tongren Hospital

Phase 2 Not yet recruiting
260 enrolled
Head & Neck

Head and Neck Neoplasms

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