Clinical Trials

166 enrolled 15 charts

Head and Neck Neoplasms, Laryngeal Diseases

NCT03040999 2026-02-04

KEYNOTE-412

804 enrolled 20 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01856478 2026-01-12

LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

340 enrolled 23 charts

Head and Neck Neoplasms

NCT03358472 2025-12-03

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

89 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04338399 2025-11-17

BURAN

487 enrolled

Head and Neck Neoplasms

NCT06256588 2025-09-25

JADE

Phase 3 Recruiting

864 enrolled

Phase 3 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03765918 2025-08-20

MK-3475-689

714 enrolled 90 charts 3 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Head and Neck Neoplasms

NCT02358031 2025-07-18

MK-3475-048

882 enrolled 50 charts 2 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Head and Neck Neoplasms

NCT01345084 2025-03-28

NICAP

Phase 3 Active not recruiting

Carcinoma, Head and Neck Neoplasms

NCT03769506 2025-01-16

ASP-1929 Photoimmunotherapy (PIT) Study in Recurrent Head/Neck Cancer for Patients Who Have Failed at Least Two Lines of Therapy

135 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04428333 2024-10-09

INDUCE-4

117 enrolled 33 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04128696 2024-07-10

INDUCE-3

315 enrolled 31 charts

Head and Neck Neoplasms, Neoplasms

NCT03689712 2023-10-24

ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients

455 enrolled 11 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis, Oral Ulcer

NCT02741570 2023-09-21

CheckMate 651

947 enrolled 19 charts

Head and Neck Neoplasms

NCT02578641 2023-06-28

VANCE

330 enrolled 18 charts

Nasopharyngeal Carcinoma, Head and Neck Neoplasms, Nasopharyngeal Neoplasms, Nose Neoplasms, Epstein-Barr Virus Infections

NCT03237325 2022-11-08

DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer

266 enrolled 11 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis

NCT00198315 2022-03-04

Medpulser Electroporation With Bleomycin Study to Treat Anterior Head and Neck Squamous Cell Carcinoma

130 enrolled

Carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasms

NCT00198328 2022-03-04

Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma

84 enrolled

Carcinoma, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Neoplasms

NCT02369874 2021-02-10

EAGLE

736 enrolled 26 charts

Head and Neck Neoplasms, Recurrence

NCT03342352 2019-12-20

Nivolumab Plus Epacadostat in Combination With Chemotherapy Versus the EXTREME Regimen in Squamous Cell Carcinoma of the Head and Neck (CheckMate 9NA/ECHO-310)

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03386838 2019-04-18

An Immuno-therapy Study of Nivolumab in Combination With Experimental Medication BMS-986205 Compared to Standard of Care EXTREME Regimen in First-line Recurrent/Metastatic Squamous Cell Carcinoma of Head and Neck

Head and Neck Neoplasms

NCT02131155 2019-03-01

LUX-Head & Neck 4: Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy

36 enrolled 6 charts

Head and Neck Neoplasms

NCT00995293 2018-03-02

Taxotere (Docetaxel) New Indication: Squamous Cell Carcinoma of the Head and Neck (SCCHN) Treatment Registration Trial

240 enrolled

Head and Neck Neoplasms

NCT01345682 2018-02-15

LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

483 enrolled 21 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT01345669 2017-12-07

LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy

617 enrolled 13 charts

Head and Neck Neoplasms

NCT00131638 2016-12-16

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer

241 enrolled

Head and Neck Neoplasms, Neoplasms, Stomatitis

NCT00412217 2016-11-25

A Study of Erlotinib (Tarceva) in Participants With Resected Head and Neck Squamous Cell Cancer

94 enrolled 6 charts

Head and Neck Neoplasms

NCT00101582 2016-09-27

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

188 enrolled 19 charts

Head & NeckOther

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Stomatitis, Xerostomia, Oral Ulcer, Mucositis

NCT00174837 2016-05-26

TRACE

317 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01161498 2016-02-08

Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer

5 enrolled 8 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02630264 2015-12-15

E10A for the Treatment of Squamous Cell Carcinoma of the Head and Neck

Phase 3 Unknown

540 enrolled

Head and Neck Neoplasms

NCT00122460 2014-07-23

Cetuximab (Erbitux) in Combination With Cisplatin or Carboplatin and 5-Fluorouracil in the First Line Treatment of Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (EXTREME)

442 enrolled 18 charts

Head and Neck Neoplasms

NCT00424255 2014-07-18

Study Of Adjuvant Lapatinib In High-Risk Head And Neck Cancer Subjects After Surgery

688 enrolled 19 charts

Head and Neck Neoplasms

NCT02183246 2014-07-08

Porfiromycin Used as an Adjuvant to Radiation Therapy in Postoperative Head and Neck Cancer Patients

3 enrolled

Head and Neck Neoplasms

NCT01701349 2014-05-01

FACT2

EndocrineHead & Neck

Head and Neck Neoplasms, Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00460265 2014-03-07

SPECTRUM

658 enrolled 17 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00382031 2013-10-15

Zalutumumab in Patients With Non-curable Head and Neck Cancer

286 enrolled 12 charts

Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT00574860 2013-09-20

EN3285 for the Prevention or Delay of Oral Mucositis in Patients With Head and Neck Cancer

240 enrolled

Head and Neck Neoplasms, Stomatitis

NCT00017511 2012-05-16

Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer

CNSHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00415194 2011-06-28

A Study for Patients With Head and Neck Cancer

795 enrolled 19 charts

Head and Neck Neoplasms

NCT00790322 2010-02-19

Efficacy and Safety Study of SBG vs Placebo in Head and Neck Cancer Patients Undergoing Radiation Therapy

130 enrolled

Head and Neck Neoplasms, Neoplasms, Stomatitis

NCT00094081 2010-02-15

Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer

861 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases

NCT00273546 2009-04-29

Induction Chemotherapy Comparing Taxotere® Cisplatin and 5-Fluorouracil (TPF) With Standard Cisplatin and 5-Fluorouracil (PF) Followed by Chemoradiation in Locally Advanced Head and Neck Cancer

500 enrolled

Head and Neck Neoplasms, Neoplasms

NCT00050388 2008-06-24

Phase II Trial of Allovectin-7® for Head and Neck Cancer