Clinical Trials

24 enrolled

Phase NA Not yet recruiting

Head and Neck Neoplasms

NCT07606287 2026-05-26

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

4,000 enrolled

BreastCNSDermatologicGastrointestinalHead & Neck

Breast Neoplasms, Endocrine Gland Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Skin Neoplasms, Soft Tissue Neoplasms, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT01098955 2026-05-22

Smoking Cessation Treatment for Head & Neck Cancer Patients

Phase EARLY_PHASE1 Active not recruiting

51 enrolled

Head and Neck Neoplasms, Neoplasms, Smoking Cessation

NCT02308072 2026-05-22

ORCA-2

Phase 1 Completed

16 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT03336606 2026-05-22

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Phase 1 Completed

13 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Squamous Cell

NCT03646461 2026-05-22

Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC

Phase 2 Terminated

5 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04169074 2026-05-22

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

Phase 2 Terminated

7 enrolled 14 charts

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT04858269 2026-05-22

First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients

32 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT07601737 2026-05-22

Nimotuzumab Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

182 enrolled

Phase NA Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02253238 2026-05-20

Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients

427 enrolled

Dehydration, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms

NCT03491176 2026-05-20

Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer

Active not recruiting

100 enrolled

Head and Neck Neoplasms

NCT03494322 2026-05-20

EACH

16 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT07264075 2026-05-20

ILLUMINE

Phase 3 Recruiting

780 enrolled

BreastCNSGastrointestinalGenitourinaryHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07407582 2026-05-20

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

Phase 1/2 Recruiting

25 enrolled

GenitourinaryHead & Neck

Head and Neck Neoplasms, Neoplasms, Testicular Neoplasms, Hearing Loss

NCT05184790 2026-05-19

LEARN

Recruiting

300 enrolled

Arrhythmias, Cardiac, Brain Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Spinal Neoplasms

NCT05218824 2026-05-19

CHIRP

Completed

32 enrolled

Head and Neck Neoplasms

NCT05743569 2026-05-19

3D Specimen Maps for RT Planning

Active not recruiting

13 enrolled

Phase NA Enrolling by invitation

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07595666 2026-05-19

Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.

1,600 enrolled

CNSEndocrineHead & Neck

Amyotrophic Lateral Sclerosis, Brain Neoplasms, Dementia, Epilepsy, Head and Neck Neoplasms, Movement Disorders, Neuroblastoma, Parathyroid Neoplasms, Parkinson Disease, Pituitary Neoplasms, Lewy Body Disease

NCT07596355 2026-05-19

H&NANCE

Not yet recruiting

283 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Leukoplakia, Neoplasms

NCT06904365 2026-05-18

OvAR-Y

Active not recruiting

10 enrolled

Anus Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Rectal Neoplasms, Sarcoma, Stomach Neoplasms, Uterine Neoplasms

NCT07589049 2026-05-15

GATEWAY

Phase 2 Not yet recruiting

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01235052 2026-05-14

MISORL

Phase NA Completed

16 enrolled

Head and Neck Neoplasms

NCT05278039 2026-05-14

Training Swallowing Initiation During Expiration

Phase NA Completed

88 enrolled

Squamous Cell Carcinoma of Head and Neck, Deglutition Disorders, Head and Neck Neoplasms

NCT07557225 2026-05-14

18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

200 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, von Hippel-Lindau Disease, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma

NCT02841748 2026-05-13

A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay Study

100 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03632200 2026-05-13

NUTRIMAX

60 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Head and Neck Neoplasms, Nutrition Disorders

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

Phase 1 Recruiting

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT07583914 2026-05-13

Safety, Tolerability, and Preliminary Antitumor Activity of Non-Cationic Peptide-CD47 siRNA in Advanced Solid Tumors

Phase 1 Not yet recruiting

9 enrolled

Head and Neck Neoplasms, Neoplasm Metastasis

NCT04261192 2026-05-12

ORGAVADS

Recruiting

120 enrolled

Head and Neck Neoplasms

NCT05420948 2026-05-12

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07149207 2026-05-12

Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

30 enrolled

Phase NA Active not recruiting

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms

NCT07283861 2026-05-12

Axoguard HA Plus Nerve Protector to Reduce Post-operative Neck and Shoulder Dysfunction in Patients Undergoing Neck Dissection

90 enrolled

Phase 2 Active not recruiting

Head and Neck Neoplasms

NCT04373642 2026-05-11

QUADSHOT

30 enrolled

Head and Neck Neoplasms

NCT06997068 2026-05-11

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

25 enrolled

BreastDermatologicGastrointestinalHead & NeckThoracic

Carcinoma, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT07524114 2026-05-11

SHERLOCK

Recruiting

7,000 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Unknown Primary, Urogenital Neoplasms, Neoplasm, Residual

NCT02296684 2026-05-08

Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma

67 enrolled 15 charts

DermatologicGenitourinaryHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04146064 2026-05-08

Breathomics as Predictive Biomarker for Checkpoint Inhibitor Response

Completed

190 enrolled

Carcinoma, Transitional Cell, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma

NCT05754814 2026-05-08

SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Malignant Lymph Nodes

Completed

20 enrolled

Head & NeckLymphoid

Head and Neck Neoplasms, Lymphatic Metastasis, Lymphoma

NCT06660017 2026-05-08

Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse

Phase 2 Not yet recruiting

62 enrolled

Phase EARLY_PHASE1 Recruiting

Head and Neck Neoplasms

NCT06819228 2026-05-08

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

18 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Mouth Neoplasms, Tongue Neoplasms

NCT06915454 2026-05-08

High-Resolution PET-CT Imaging for Surgical Margin Visualization

50 enrolled

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Mouth Neoplasms, Neoplasms, Tongue Neoplasms

NCT07484139 2026-05-08

NEO COMBAT XL

26 enrolled

Phase NA Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07558096 2026-05-08

Evaluating Avive+ Soft Tissue Matrix for Prevention of Superficial Radial Nerve Morbidity Following Radial Forearm Free Flap Harvest

80 enrolled

Head and Neck Neoplasms, Neuralgia

NCT04313504 2026-05-07

Study Evaluating the Efficacy of Niraparib and Dostarlimab (TSR-042) in Recurrent/Metastatic HNSCC

10 enrolled 9 charts

BreastGastrointestinalHead & Neck

Head and Neck Neoplasms

NCT04541381 2026-05-07

The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care

Phase NA Suspended

860 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Dihydropyrimidine Dehydrogenase Deficiency

NCT07110142 2026-05-07

T-PROSE

40 enrolled

Head and Neck Neoplasms, Mouth Neoplasms

NCT07573956 2026-05-07

Radiotherapy

Phase 2/3 Recruiting

369 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03355560 2026-05-06

Adjuvant Nivolumab After Salvage Resection in Head and Neck Cancer Patients Previously Treated With Definitive Therapy

39 enrolled 11 charts

Head and Neck Neoplasms

NCT03506451 2026-05-06

PaRTNer

Phase NA Completed

60 enrolled