Clinical Trials

80 enrolled

Head and Neck Neoplasms

NCT07445048 2026-04-17

Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma

Phase 3 Recruiting

370 enrolled

Phase 3 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01266044 2026-04-16

Controlled Trial Of Acupuncture To Prevent Radiation-Induced Xerostomia

435 enrolled

Phase NA Active not recruiting

Head and Neck Neoplasms, Oropharyngeal Neoplasms, Xerostomia

NCT02662907 2026-04-16

Cough, Expiratory Training, and Chronic Aspiration After Head and Neck Radiotherapy

175 enrolled

Head and Neck Neoplasms

NCT03145077 2026-04-16

Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosing Osteoradionecrosis in Patients With Head and Neck Cancer That Is Primary, Has Come Back, or Has Spread to Other Places in the Body

1,400 enrolled

Head and Neck Neoplasms, Osteoradionecrosis

NCT07101432 2026-04-16

Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

Phase 1 Recruiting

33 enrolled

Phase 2 Not yet recruiting

Head and Neck Neoplasms

NCT07361133 2026-04-16

Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer

120 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence

NCT00076310 2026-04-15

OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell Cancer

50 enrolled 11 charts

Phase NA Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT03114501 2026-04-15

Dyadic Yoga Intervention for Patient With Head and Neck Cancer Undergoing Radiotherapy and Their Family Caregivers

236 enrolled

Head and Neck Neoplasms

NCT03953352 2026-04-15

GIRAFE

Phase NA Withdrawn

Head and Neck Neoplasms

NCT04003051 2026-04-15

Web-Based Program in Helping Patients With Head and Neck Cancer Adhere to Swallowing Exercises and Coping Strategies

300 enrolled

Phase NA Active not recruiting

Head and Neck Neoplasms, Trismus

NCT04208490 2026-04-15

HN-STAR

357 enrolled

Phase 3 Active not recruiting

Head and Neck Neoplasms

NCT05187091 2026-04-15

SWOAR

136 enrolled

Deglutition Disorders, Head and Neck Neoplasms

NCT07213934 2026-04-15

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

Phase 1/2 Recruiting

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07524894 2026-04-15

SNIFF

126 enrolled

Phase NA Not yet recruiting

Head and Neck Neoplasms

NCT07531563 2026-04-15

C-Head-002

504 enrolled

Head and Neck Neoplasms

NCT04449445 2026-04-14

Perioperative Nutritional Optimization in Head and Neck Cancer Patients

4 enrolled

Head and Neck Neoplasms

NCT04704453 2026-04-14

TEC-ORL

Phase 2 Completed

13 enrolled

Head and Neck Neoplasms, Neuralgia

NCT05576974 2026-04-14

A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)

120 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Unknown Primary

NCT07528495 2026-04-14

Eliminate

Phase 2/3 Recruiting

396 enrolled

Head and Neck Neoplasms

NCT03102229 2026-04-13

RAMPART

GastrointestinalHead & NeckThoracic

Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Stomach Neoplasms

NCT03115398 2026-04-13

A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery

CNSGastrointestinalGynecologicHead & NeckThoracic

166 enrolled

Brain Neoplasms, Uterine Cervical Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT04470024 2026-04-13

Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC

Phase 1 Recruiting

56 enrolled

Head and Neck Neoplasms

NCT05313191 2026-04-13

ReRT

BreastCNSGastrointestinalGenitourinaryHead & Neck

1,800 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Neoplasms, Prostatic Neoplasms, Central Nervous System Neoplasms

NCT05874492 2026-04-13

FIBROTHERME

110 enrolled

BreastHead & Neck

Breast Neoplasms, Fibrosis, Head and Neck Neoplasms

NCT06676943 2026-04-13

eXcision

57 enrolled

Head and Neck Neoplasms

NCT07149207 2026-04-13

Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

30 enrolled

Phase 1/2 Not yet recruiting

Margins of Excision, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms

NCT07407582 2026-04-13

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

25 enrolled

GenitourinaryHead & Neck

Head and Neck Neoplasms, Neoplasms, Testicular Neoplasms, Hearing Loss

NCT04938609 2026-04-09

Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC)

28 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05420948 2026-04-09

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

Phase 2 Suspended

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07242690 2026-04-08

PET-CT Imaging With PCD-CT

Phase NA Suspended

20 enrolled

Head and Neck Neoplasms

NCT07040969 2026-04-07

Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

70 enrolled

Head and Neck Neoplasms

NCT06531083 2026-04-06

PRECISE

30 enrolled

Phase 1/2 Active not recruiting

Head and Neck Neoplasms, Trismus

NCT06919666 2026-04-06

NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

29 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06905561 2026-04-03

Topical Diclofenac for Prevention of Radiation-induced Dermatitis

Phase 3 Not yet recruiting

156 enrolled

BreastHead & Neck

Breast Neoplasms, Head and Neck Neoplasms, Radiodermatitis

NCT07264075 2026-04-02

ILLUMINE

780 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07506902 2026-04-02

DART-HN

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05315570 2026-04-01

BD4QoL

410 enrolled

Head and Neck Neoplasms

NCT05318027 2026-04-01

ChatBot and Activity Monitoring in Patients Undergoing Chemoradiotherapy

GastrointestinalHead & NeckThoracic

70 enrolled

Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT06137274 2026-04-01

Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC

35 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT06915727 2026-04-01

An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors

Phase 3 Recruiting

20 enrolled

GynecologicHead & Neck

Head and Neck Neoplasms, Pelvic Neoplasms

NCT07467083 2026-04-01

Development and Application of a Nurse-Led Preemptive Symptom Management Protocol for Head and Neck Cancer Patients Undergoing Radiation Therapy

Phase 3 Recruiting

170 enrolled

Head and Neck Neoplasms

NCT05696288 2026-03-31

OPTINOSE

160 enrolled

Head and Neck Neoplasms

NCT05980000 2026-03-31

Rambro2

37 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06110195 2026-03-31

Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer

Phase 1 Terminated

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02517125 2026-03-30

TORS

100 enrolled

Head and Neck Neoplasms

NCT04722523 2026-03-30

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

Phase 1 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06708754 2026-03-30

PBM-LEF

60 enrolled

Radiation Fibrosis Syndrome, Head and Neck Neoplasms

NCT06907095 2026-03-30

LEAH

5,909 enrolled