Announcements Trials
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Phase

Phase NA 1Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Breast Neoplasms 19Recurrence 4Neoplasm Metastasis 4Hereditary Sensory and Autonomic Neuropathies 4Squamous Cell Carcinoma of Head and Neck 3Neoplasms 3Multiple Endocrine Neoplasia Type 1 3Head and Neck Neoplasms 3Hyperglycemia 2Head and Neck Squamous Cell Cancer 2Uveal Melanoma 1Triple Negative Breast Neoplasms 1Stomach Neoplasms Esophageal Neoplasms Metastatic Gastric Cancer Mutated PI3KCA Protein Overexpressed HER2 Protein 1Pre-menopausal Breast Cancer 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Multiple Myeloma 1Melanoma 1Kidney Neoplasms 1Esophageal Squamous Cell Carcinoma 1Esophageal Neoplasms 1Colorectal Neoplasms 1Carcinoma, Renal Cell 1Advanced and Selected Solid Tumors 1Advanced Solid Tumors With an Alteration of the PIK3CA Gene 1Advanced Solid Tumor 1Adenocarcinoma of Lung 1Acrocephalosyndactylia 13rd Line GIST 1

Interventions

Cetuximab 2Alpelisib 2rocakinogene sifuplasmid 1cabozantinib 1VGX-3100 1Radiotherapy, Intensity-Modulated 1Metformin 1MEDI0457 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Head and Neck Squamous Cell Cancer × Alpelisib × Clear all
NCT03138070 2026-01-28

A Window of Opportunity Study to Assess the Modulation of Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) By Preoperative Treatment With BYL719

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Phase NA Completed
15 enrolled
Head & Neck

Head and Neck Squamous Cell Cancer

NCT02282371 2021-10-26

Cetuximab + BYL719 + IMRT (Intensity-Modulated Radiation Therapy) in Stage III/IVB Head and Neck Squamous Cell Cancer (HNSCC)

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
16 enrolled
Head & Neck

Head and Neck Squamous Cell Cancer

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