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Phase

Phase 1 2Phase NA 1Phase EARLY_PHASE1 1Phase 1/2 1

Status

Completed 5Unknown 4

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 5Observational 1

Sponsor

Cancer Type

Head & Neck 5

Conditions

Breast Neoplasms 5004Neoplasms 4197Prostatic Neoplasms 2428Carcinoma, Non-Small-Cell Lung 2265Colorectal Neoplasms 2053Lung Neoplasms 1705Multiple Myeloma 1459Lymphoma 1405Leukemia, Myeloid, Acute 1382Neoplasm Metastasis 1374Melanoma 1270Pancreatic Neoplasms 1200Leukemia 1196Ovarian Neoplasms 1192Lymphoma, Non-Hodgkin 1132Precursor Cell Lymphoblastic Leukemia-Lymphoma 1091Head and Neck Neoplasms 1056Leukemia, Lymphocytic, Chronic, B-Cell 994Lymphoma, Follicular 897Colonic Neoplasms 895Brain Neoplasms 876Stomach Neoplasms 857Recurrence 853Carcinoma, Hepatocellular 846Glioblastoma 841Lymphoma, Large B-Cell, Diffuse 771Rectal Neoplasms 759Uterine Cervical Neoplasms 728Carcinoma, Renal Cell 705Hodgkin Disease 698

Interventions

Cetuximab 2Alpelisib 2rocakinogene sifuplasmid 1cabozantinib 1VGX-3100 1Radiotherapy, Intensity-Modulated 1Metformin 1MEDI0457 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Interventional × Head and Neck Squamous Cell Cancer × Clear all
NCT03138070 2026-01-28

A Window of Opportunity Study to Assess the Modulation of Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) By Preoperative Treatment With BYL719

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Phase NA Completed
15 enrolled
Head & Neck

Head and Neck Squamous Cell Cancer

NCT02083692 2025-05-15

Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling

Thomas Jefferson University

Phase EARLY_PHASE1 Completed
50 enrolled
Head & Neck

Head and Neck Squamous Cell Cancer

NCT03667482 2024-07-23

Cabozantinib in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Cancer

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
20 enrolled
Head & Neck

Head and Neck Squamous Cell Cancer

NCT02282371 2021-10-26

Cetuximab + BYL719 + IMRT (Intensity-Modulated Radiation Therapy) in Stage III/IVB Head and Neck Squamous Cell Cancer (HNSCC)

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
16 enrolled
Head & Neck

Head and Neck Squamous Cell Cancer

NCT02163057 2021-01-22

Study of HPV Specific Immunotherapy in Participants With HPV Associated Head and Neck Squamous Cell Carcinoma

Inovio Pharmaceuticals

Phase 1/2 Completed
22 enrolled 14 charts
Head & Neck

Head and Neck Squamous Cell Cancer

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