Announcements Trials
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Phase

Phase 1 2

Status

Recruiting 1Completed 1Available 1

Sponsor Class

INDUSTRY 2OTHER 1

Study Type

Interventional 2Expanded_access 1

Sponsor

Cancer Type

Genitourinary 1Gastrointestinal 1

Conditions

Mesothelioma, Malignant 5Hepatoblastoma 5Ototoxicity 4Medulloblastoma 4Central Nervous System Neoplasms 4Peritoneal Neoplasms 3Ovarian Neoplasms 3Hearing Loss 3Gastrointestinal Neoplasms 3Drug-Related Side Effects and Adverse Reactions 3Testicular Neoplasms 2Stomach Neoplasms 2Sarcoma 2Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Liver Neoplasms 2Glioma 2Brain Neoplasms 2Astrocytoma 2Adrenocortical Carcinoma 2Thrombocytopenia 1Teratoma 1Seminoma 1Rhabdomyosarcoma 1Rectal Neoplasms 1Pelvic Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1

Interventions

sodium thiosulfate 3ebselen 2Ankle Brachial Index 2Acetylcysteine 2Tomography, X-Ray Computed 1Sodium Chloride 1Saline Solution 1Ringer's Lactate 1Radiotherapy 1Radiosurgery 1Platinum 1Ofloxacin 1Magnetic Resonance Spectroscopy 1Magnetic Resonance Imaging 1Hyaluronic Acid 1Hearing Tests 1Hearing 1Genetic Association Studies 1Ear Protective Devices 1Drug Therapy 1Cisplatin 1Chemoradiotherapy 1Carboplatin 1Audiometry, Pure-Tone 1Atorvastatin 1Acoustic Impedance Tests 11,2-diaminocyclohexaneplatinum II citrate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Hearing Loss × sodium thiosulfate × Clear all
NCT07218913 2026-04-17

Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors

City of Hope Medical Center

Phase 1 Recruiting
44 enrolled
Genitourinary

Testicular Neoplasms, Seminoma, Hearing Loss

NCT04262336 2023-07-06

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

Decibel Therapeutics

Phase 1 Completed
22 enrolled

Ototoxicity, Hearing Loss

NCT04132882 2021-09-16

A Compassionate Use Program to Provide Access to Sodium Thiosulfate

TRPHARM

Available
Gastrointestinal

Hepatoblastoma, Hearing Loss

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