Announcements Trials
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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Withdrawn 2Completed 2Recruiting 1Enrolling by invitation 1Available 1

Sponsor Class

OTHER 30INDUSTRY 7NIH 2FED 2OTHER_GOV 1

Study Type

Interventional 4Observational 2Expanded_access 1

Sponsor

Cancer Type

CNS 2Thoracic 1Head & Neck 1Gastrointestinal 1

Conditions

Neoplasms 3216Carcinoma, Non-Small-Cell Lung 2729Breast Neoplasms 2551Colorectal Neoplasms 1463Prostatic Neoplasms 1307Neoplasm Metastasis 1301Multiple Myeloma 1112Melanoma 1103Ovarian Neoplasms 1006Lung Neoplasms 945Recurrence 924Leukemia, Myeloid, Acute 879Pancreatic Neoplasms 833Lymphoma, Non-Hodgkin 767Lymphoma 713Stomach Neoplasms 692Carcinoma, Renal Cell 660Carcinoma, Hepatocellular 647Leukemia, Lymphocytic, Chronic, B-Cell 560Squamous Cell Carcinoma of Head and Neck 550Lymphoma, Follicular 515Head and Neck Neoplasms 490Glioblastoma 473Small Cell Lung Carcinoma 447Lymphoma, Large B-Cell, Diffuse 440Triple Negative Breast Neoplasms 436Advanced Solid Tumors 432Leukemia 426Uterine Cervical Neoplasms 420Urinary Bladder Neoplasms 405

Interventions

sodium thiosulfate 2ebselen 2Sodium Chloride 1Hyaluronic Acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
INDUSTRY × Hearing Loss × Clear all
NCT01451853 2026-06-03

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Sound Pharmaceuticals, Incorporated

Phase 2 Withdrawn
Head & NeckThoracic

Ototoxicity, Deafness, Head and Neck Neoplasms, Lung Neoplasms, Tinnitus, Hearing Loss

NCT06517888 2026-04-06

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

Akouos, Inc.

Phase 1/2 Recruiting
27 enrolled
CNS

Neuroma, Acoustic, Hearing Loss

NCT07503613 2026-04-06

Long Term Follow-up Study of AAVAnc80-antiVEGF Gene Therapy

Akouos, Inc.

Enrolling by invitation
100 enrolled
CNS

Neuroma, Acoustic, Hearing Loss

NCT04262336 2023-07-06

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

Decibel Therapeutics

Phase 1 Completed
22 enrolled

Ototoxicity, Hearing Loss

NCT02778295 2023-02-13

BioFabry

CENTOGENE GmbH Rostock

Withdrawn

Angiokeratoma, Fabry Disease, Hearing Loss, Renal Insufficiency, Chronic

NCT04132882 2021-09-16

A Compassionate Use Program to Provide Access to Sodium Thiosulfate

TRPHARM

Available
Gastrointestinal

Hepatoblastoma, Hearing Loss

NCT01452607 2016-06-29

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Sound Pharmaceuticals, Incorporated

Phase 1 Completed
32 enrolled

Neoplasms, Hearing Loss

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