Clinical Trials Browser

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hearing Loss

NCT07407582 2026-06-05

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

Phase 1/2 Recruiting

25 enrolled

GenitourinaryHead & Neck

Head and Neck Neoplasms, Neoplasms, Testicular Neoplasms, Hearing Loss

NCT01451853 2026-06-03

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Phase 2 Withdrawn

Head & NeckThoracic

Ototoxicity, Deafness, Head and Neck Neoplasms, Lung Neoplasms, Tinnitus, Hearing Loss

NCT07622407 2026-06-03

TIMELY REHAB

Phase NA Not yet recruiting

74 enrolled

Head & Neck

Ototoxicity, Deglutition Disorders, Head and Neck Neoplasms, Hearing Loss, Sensorineural, Tinnitus, Hearing Loss, Drug-Related Side Effects and Adverse Reactions

NCT07420751 2026-04-28

Assessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-Schwannomatosis

Phase NA Active not recruiting

18 enrolled

CNS

Neurofibromatosis 2, Hearing Loss

NCT07218913 2026-04-17

Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors

Phase 1 Recruiting

44 enrolled

Genitourinary

Testicular Neoplasms, Seminoma, Hearing Loss

NCT06036407 2026-04-14

HEAR

Phase NA Completed

476 enrolled

Ototoxicity, Neoplasms, Hearing Loss

NCT06517888 2026-04-06

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

Phase 1/2 Recruiting

27 enrolled

CNS

Neuroma, Acoustic, Hearing Loss

NCT05789316 2026-01-12

Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)

Phase NA Completed

55 enrolled

Head & Neck

Ototoxicity, Head and Neck Neoplasms, Hearing Loss

NCT05582551 2025-12-22

Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

Phase NA Recruiting

146 enrolled

Neoplasms, Peripheral Nervous System Diseases, Hearing Loss

NCT02310399 2025-10-30

Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves

Phase NA Recruiting

20 enrolled

Deafness, Hearing Loss

NCT06894927 2025-05-30

HSA50+

Phase NA Enrolling by invitation

330 enrolled

Presbycusis, Hearing Loss

NCT04609982 2024-08-21

SSNHL in Head & Neck Cancer Patients

Phase NA Withdrawn

Hearing Loss

NCT06016335 2023-12-19

MRI-based Synthetic CT Images of the Head and Neck

Phase NA Completed

80 enrolled

Head & Neck

Cholesteatoma, Head and Neck Neoplasms, Sinusitis, Hearing Loss

NCT04291209 2023-09-06

Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.

Phase 1/2 Unknown

80 enrolled

Deafness, Ear Diseases, Hearing Loss, Sensorineural, Hearing Loss

NCT04262336 2023-07-06

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

Phase 1 Completed

22 enrolled

Ototoxicity, Hearing Loss

NCT02094625 2023-04-18

NAC to Prevent Cisplatin-induced Hearing Loss

Phase 1 Completed

52 enrolled

GastrointestinalSarcoma

Liver Neoplasms, Osteosarcoma, Neuroectodermal Tumors, Primitive, Hearing Loss

NCT02716376 2022-07-26

Treatment and Prevention of Middle Ear Morbidity in Head and Neck Cancer Patients Following Radiotherapy

Phase NA Completed

30 enrolled

Head & Neck

Head and Neck Neoplasms, Otitis Media, Otitis Media with Effusion, Hearing Loss

NCT04505696 2020-10-08

Providing Speech Therapy Awareness in Private Schools

Phase NA Completed

138 enrolled

Head & Neck

Developmental Disabilities, Communication Disorders, Deglutition Disorders, Head and Neck Neoplasms, Language Development Disorders, Language Disorders, Speech, Stuttering, Hearing Loss

NCT01864291 2020-06-02

ABI

Phase NA Terminated

9 enrolled 10 charts

Deafness, Hearing Loss

NCT01736267 2020-05-06

Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects

Phase NA Terminated

3 enrolled 8 charts

Deafness, Hearing Loss

NCT01969370 2017-05-03

NCGENES

Phase NA Completed

645 enrolled

Congenital Abnormalities, Cardiovascular Diseases, Neoplasms, Neurologic Manifestations, Neurodegenerative Diseases, Hearing Loss

NCT01452607 2016-06-29

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Phase 1 Completed

32 enrolled

Neoplasms, Hearing Loss

NCT00584155 2015-05-27

Protection From Cisplatin Ototoxicity by Lactated Ringers

Phase 1 Withdrawn

Ear Neoplasms, Hearing Loss

NCT00004437 2015-03-25

Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2

Phase 2 Completed

CNS

Mental Disorders, Neurologic Manifestations, Neuroma, Acoustic, Neurofibromatosis 2, Neurofibromatoses, Genetic Diseases, Inborn, Hearing Loss, Rare Diseases

Clinical Trials

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

TIMELY REHAB

Assessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-Schwannomatosis

Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors

HEAR

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)

Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves

HSA50+

SSNHL in Head & Neck Cancer Patients

MRI-based Synthetic CT Images of the Head and Neck

Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

NAC to Prevent Cisplatin-induced Hearing Loss

Treatment and Prevention of Middle Ear Morbidity in Head and Neck Cancer Patients Following Radiotherapy

Providing Speech Therapy Awareness in Private Schools

ABI

Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects

NCGENES

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Protection From Cisplatin Ototoxicity by Lactated Ringers

Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2