Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 2INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 2Other neoplasm 1Other hematologic neoplasm 1

Conditions

Carcinoma, Non-Small-Cell Lung 185Neoplasms 111Breast Neoplasms 100Colorectal Neoplasms 90Ovarian Neoplasms 72Neoplasm Metastasis 70Prostatic Neoplasms 67Multiple Myeloma 63Lung Neoplasms 59Squamous Cell Carcinoma of Head and Neck 47Endometrial Neoplasms 46Recurrence 45Pancreatic Neoplasms 43Leukemia, Lymphocytic, Chronic, B-Cell 38Small Cell Lung Carcinoma 37Stomach Neoplasms 36Carcinoma, Renal Cell 36Melanoma 33Leukemia, Myeloid, Acute 32Urinary Bladder Neoplasms 28Triple Negative Breast Neoplasms 28Lymphoma, Non-Hodgkin 27Parkinson Disease 4, Autosomal Dominant Lewy Body 26Head and Neck Neoplasms 25Lymphoma, Follicular 24Carcinoma, Hepatocellular 24Lymphoma, Large B-Cell, Diffuse 23Esophageal Neoplasms 22Advanced Solid Tumors 22Lymphoma 21

Interventions

ruxolitinib 1CPI-0610 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
INDUSTRY × Hematologic Diseases × 30 days × Clear all
NCT02158858 2026-06-04

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled 61 charts
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT05186753 2026-05-22

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Cogent Biosciences, Inc.

Phase 2 Active not recruiting
237 enrolled
Myeloid

Hematologic Diseases, Hypersensitivity, Immune Complex Diseases, Immune System Diseases, Mastocytosis, Mastocytosis, Systemic

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