Announcements Trials
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Phase

Phase 2 3

Status

Terminated 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3Plasma cell 1Myeloid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 32Myelodysplastic Syndromes 30Leukemia, Myeloid, Acute 30Multiple Myeloma 24Lymphoma, Non-Hodgkin 24Hodgkin Disease 24Lymphoma 21Leukemia 21Graft vs Host Disease 21Leukemia, Lymphocytic, Chronic, B-Cell 20Leukemia, Myelogenous, Chronic, BCR-ABL Positive 16Myeloproliferative Disorders 15Lymphoma, Mantle-Cell 15Neoplasms 14Tuberous Sclerosis 13Lymphoma, Large B-Cell, Diffuse 13Hematologic Neoplasms 12Burkitt Lymphoma 12Primary Myelofibrosis 11Lymphoma, Follicular 11Breast Neoplasms 11Waldenstrom Macroglobulinemia 10Sarcoma 10Recurrence 10Neoplasms, Plasma Cell 10Neoplasm Metastasis 10Lymphoma, B-Cell, Marginal Zone 10Leukemia, Myelomonocytic, Chronic 10Prostatic Neoplasms 9Lymphangioleiomyomatosis 9

Interventions

fludarabine 12Cyclophosphamide 11Busulfan 8Mycophenolic Acid 6Dexamethasone 6fludarabine phosphate 5Whole-Body Irradiation 5Tacrolimus 5Melphalan 5Lenalidomide 5Granulocyte Colony-Stimulating Factor 4isatuximab 3Thiotepa 3Sirolimus 3Rituximab 3Methotrexate 3Cyclosporine 3Blood Specimen Collection 3Alemtuzumab 3pomalidomide 2pembrolizumab 2daratumumab 2Vorinostat 2Stem Cell Transplantation 2Platelet Transfusion 2Ondansetron 2Interviews as Topic 2Filgrastim 2Exercise 2Etoposide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Hematologic Diseases × Sirolimus × Clear all
NCT03246906 2026-05-14

Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

Fred Hutchinson Cancer Center

Phase 2 Terminated
150 enrolled 18 charts
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Blastic Plasmacytoid Dendritic Cell Neoplasm, Hematologic Diseases, Hodgkin Disease, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases

NCT00350181 2021-09-23

Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT

Stanford University

Phase 2 Completed
11 enrolled
LymphoidOther hematologic neoplasm

Hematologic Diseases, Leukemia, Lymphoma, Non-Hodgkin

NCT01220297 2017-06-05

Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT

Stanford University

Phase 2 Terminated
3 enrolled 13 charts
LymphoidOther hematologic neoplasm

Hematologic Diseases, Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin

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