Clinical Trials

Recurrence, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05436418 2026-04-27

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Phase 1/2 Recruiting

260 enrolled

CNSClassical hematologyLymphoidOther hematologic neoplasm

Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT05735717 2026-04-06

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Phase 2 Recruiting

70 enrolled

Chromosome 7, monosomy, Anemia, Refractory, with Excess of Blasts, Chromosome Aberrations, Influenza, Human, Neurofibromatosis 1, Leukemia, Myeloid, Acute, beta-Thalassemia, Neoplasm, Residual, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT02333162 2026-03-30

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

Phase 1 Suspended

30 enrolled

Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06028828 2026-02-02

ADAPT

Phase 2 Recruiting

60 enrolled

Hematologic Neoplasms

NCT03159702 2026-01-27

Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

43 enrolled 9 charts

Phase 2 Active not recruiting

Hematologic Diseases, Multiple Myeloma, Hematologic Neoplasms

NCT04395222 2026-01-06

Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation

21 enrolled 15 charts

Hematologic Neoplasms

NCT07052370 2025-12-31

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Phase 1 Recruiting

30 enrolled

Phase 2 Active not recruiting

Hematologic Neoplasms

NCT01810588 2025-09-02

Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation

270 enrolled 13 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Lymphoma, Myeloproliferative Disorders, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT04098393 2025-06-29

Giving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation

Phase 1 Active not recruiting

39 enrolled

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Hematologic Neoplasms

NCT01350258 2025-05-31

Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps

Phase 1/2 Terminated

8 enrolled 8 charts

Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT02880293 2024-12-06

Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor

Phase NA Completed

44 enrolled 8 charts

Hematologic Neoplasms

NCT00019097 2024-03-04

Vaccine Therapy in Treating Patients With Multiple Myeloma

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Neoplasms, Hematologic Neoplasms, Genetic Diseases, Inborn, Neoplasms, Plasma Cell

NCT03852407 2022-10-12

HLA

Phase 2 Recruiting

114 enrolled

Graft vs Host Disease, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, B-Cell, Hematologic Neoplasms

NCT04282174 2022-09-27

2019-KOE-001

Phase 2 Withdrawn

LymphoidMyeloidOther hematologic neoplasm

Hematologic Diseases, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05084027 2021-10-27

Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT

Phase 2 Unknown

50 enrolled

Classical hematologyOther hematologic neoplasm

Hematologic Neoplasms

NCT03609827 2021-10-04

Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Completed

25 enrolled

Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Immunologic Deficiency Syndromes, Thalassemia, Hematologic Neoplasms

NCT01025778 2021-02-21

Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemia

7 enrolled

Graft vs Host Disease, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01010217 2020-03-25

Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

176 enrolled 18 charts

Anemia, Aplastic, Hematologic Diseases, Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00439556 2019-09-10

Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant

40 enrolled 11 charts

Lymphoma, Hematologic Neoplasms

NCT00997386 2019-09-09

ALBUM

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

16 enrolled 7 charts

Anemia, Aplastic, Hemoglobinuria, Paroxysmal, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Hematologic Neoplasms, Primary Myelofibrosis

NCT02199041 2018-02-07

Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen

Phase 2 Terminated

24 enrolled 17 charts

Hematologic Neoplasms

NCT00185614 2018-01-18

Non-myeloablative Allogeneic Transplantation for the Treatment of Multiple Myeloma

63 enrolled 13 charts

Multiple Myeloma, Hematologic Neoplasms

NCT00176839 2017-12-05

Stem Cell Transplantation for Hematological Malignancies

Phase 2/3 Terminated

11 enrolled 12 charts

LymphoidMyeloidOther hematologic neoplasmSarcoma

Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02259348 2017-05-30

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Phase 2 Terminated

12 enrolled 12 charts

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Sarcoma, Myeloid, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile

NCT01471067 2017-04-28

Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

Phase 1 Completed

33 enrolled

LymphoidMyeloidOther hematologic neoplasm

Pathologic Complete Response, Histiocytosis, Langerhans-Cell, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Philadelphia Chromosome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00824135 2017-01-02

Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic Malignancies

Phase 1 Completed

34 enrolled

Hematologic Neoplasms

NCT00133367 2016-07-25

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

LymphoidOther hematologic neoplasmPlasma cell

32 enrolled

Graft vs Host Disease, Hodgkin Disease, Leukemia, Myeloid, Lymphoma, Non-Hodgkin, Multiple Myeloma, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00618969 2016-03-03

Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

2 enrolled

Anemia, Aplastic, Hemoglobinuria, Paroxysmal, Hodgkin Disease, Leukemia, Lymphoma, Non-Hodgkin, Multiple Myeloma, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT00202917 2014-05-29

Haploidentical Transplantation With CD3/CD19 Depleted Grafts in Patients With Hematologic Malignancies

Phase 1/2 Completed

61 enrolled

Hematologic Neoplasms

NCT00890500 2013-10-08

Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.

Phase 1 Completed

12 enrolled

Hematologic Neoplasms

NCT00017680 2008-06-09

Study of High-Dose Melphalan and Autologous Stem Cell Transplantation in Patients With Primary Light Chain Amyloidosis

25 enrolled