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Phase

Phase 1 3Phase 1/2 1

Status

Completed 4Not yet recruiting 3Terminated 1

Sponsor Class

INDUSTRY 3OTHER_GOV 1

Study Type

Interventional 4Observational 1

Sponsor

Cancer Type

Lymphoid 1Gastrointestinal 1

Conditions

Breast Neoplasms 5004Neoplasms 4197Prostatic Neoplasms 2428Carcinoma, Non-Small-Cell Lung 2265Colorectal Neoplasms 2053Lung Neoplasms 1705Multiple Myeloma 1459Lymphoma 1405Leukemia, Myeloid, Acute 1382Neoplasm Metastasis 1374Melanoma 1270Pancreatic Neoplasms 1200Leukemia 1196Ovarian Neoplasms 1192Lymphoma, Non-Hodgkin 1132Precursor Cell Lymphoblastic Leukemia-Lymphoma 1091Head and Neck Neoplasms 1056Leukemia, Lymphocytic, Chronic, B-Cell 994Lymphoma, Follicular 897Colonic Neoplasms 895Brain Neoplasms 876Stomach Neoplasms 857Recurrence 853Carcinoma, Hepatocellular 846Glioblastoma 841Lymphoma, Large B-Cell, Diffuse 771Rectal Neoplasms 759Uterine Cervical Neoplasms 728Carcinoma, Renal Cell 705Hodgkin Disease 698

Interventions

copanlisib 1alisporivir 1Trabectedin 1Raltegravir Potassium 1Dexamethasone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Interventional × Hepatic Insufficiency × Clear all
NCT01022476 2026-04-06

LIVERAL

ANRS, Emerging Infectious Diseases

Phase 1/2 Completed
14 enrolled
Gastrointestinal

Hepatitis B, Hepatitis C, Carcinoma, Hepatocellular, HIV Infections, Liver Failure, Hepatic Insufficiency

NCT03172884 2021-04-28

Study of Copanlisib in Hepatic or Renal Impairment

Bayer

Phase 1 Completed
30 enrolled 20 charts

Hepatic Insufficiency, Renal Insufficiency

NCT01860326 2016-04-28

Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects

Debiopharm International SA

Phase 1 Completed
32 enrolled
Lymphoid

Lymphoma, Follicular, Hepatic Insufficiency

NCT01273493 2016-02-15

A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction

Janssen Research & Development, LLC

Phase 1 Completed
15 enrolled

Liver Diseases, Neoplasm Metastasis, Hepatic Insufficiency

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