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Phase

Phase 1 1

Status

Terminated 1Recruiting 1Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Hematologic Neoplasms 6Leukemia, Myeloid, Acute 5Lymphoma 3Rhabdoid Tumor 2Osteosarcoma 2Neuroblastoma 2Myelodysplastic Syndromes 2Multiple Myeloma 2Wilms Tumor 1Teratoma 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Sarcoma 1Rhabdomyosarcoma 1Recurrence 1Pyloric Stenosis, Hypertrophic 1Prostatic Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Pinealoma 1Neurofibrosarcoma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Germ Cell and Embryonal 1Metabolic Diseases 1Melanoma 1Medulloblastoma 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Non-Hodgkin 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Leukemia, Biphenotypic, Acute 1

Interventions

fludarabine 2Cyclophosphamide 2talazoparib 1sodium thiosulfate 1irinotecan sucrosofate 1fludarabine phosphate 1codrituzumab 1X-Rays 1Whole-Body Irradiation 1Vorinostat 1Vincristine 1Transplantation 1Temozolomide 1Tacrolimus 1Specimen Handling 1Phantoms, Imaging 1Nivolumab 1Mesna 1Melphalan 1Influenza Vaccines 1Honey 1Fluorouracil 1Doxorubicin 1Cisplatin 1Carboplatin 1Bone Density 1Biopsy 1Absorptiometry, Photon 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Hepatoblastoma × Mesna × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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