Announcements Trials
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Phase

Phase 3 3Phase EARLY_PHASE1 1

Status

Completed 2Suspended 1Recruiting 1

Sponsor Class

OTHER 3NETWORK 1

Study Type

Interventional 4Expanded_access 1

Sponsor

Cancer Type

Gastrointestinal 4Sarcoma 1Gynecologic 1Genitourinary 1CNS 1

Conditions

Mesothelioma, Malignant 5Ototoxicity 4Medulloblastoma 4Hepatoblastoma 4Central Nervous System Neoplasms 4Peritoneal Neoplasms 3Ovarian Neoplasms 3Gastrointestinal Neoplasms 3Drug-Related Side Effects and Adverse Reactions 3Testicular Neoplasms 2Stomach Neoplasms 2Sarcoma 2Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Liver Neoplasms 2Hearing Loss 2Glioma 2Brain Neoplasms 2Astrocytoma 2Adrenocortical Carcinoma 2Thrombocytopenia 1Teratoma 1Seminoma 1Rhabdomyosarcoma 1Rectal Neoplasms 1Pelvic Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1

Interventions

Cisplatin 8Carboplatin 8X-Rays 7Specimen Handling 7Phantoms, Imaging 7Magnetic Resonance Spectroscopy 6Cyclophosphamide 6Vincristine 5Nuclear Medicine Department, Hospital 5Granulocyte Colony-Stimulating Factor 5Etoposide 5Doxorubicin 5Biopsy 5sodium thiosulfate 4Melphalan 4Irinotecan 4Fluorouracil 4fludarabine 3Thiotepa 3Oxaliplatin 3Mesna 3Gemcitabine 3Filgrastim 3Busulfan 3ulixertinib 2tipifarnib 2tazemetostat 2selpercatinib 2pembrolizumab 2palbociclib 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Interventional × Hepatoblastoma × sodium thiosulfate × Clear all
NCT04478292 2026-05-04

A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy

Shanghai Children's Medical Center

Phase 3 Recruiting
330 enrolled
Gastrointestinal

Hepatoblastoma

NCT05756660 2025-10-20

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Children's Hospital Medical Center, Cincinnati

Phase EARLY_PHASE1 Suspended
33 enrolled
Gastrointestinal

Ototoxicity, Neoplasms, Germ Cell and Embryonal, Hepatoblastoma

NCT00716976 2023-11-09

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Children's Oncology Group

Phase 3 Completed
131 enrolled 18 charts 1 FDA
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Ovarian Germ Cell Cancer, Ototoxicity, Brain Neoplasms, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Hepatoblastoma

NCT00652132 2018-05-29

SIOPEL6

University of Birmingham

Phase 3 Completed
116 enrolled 1 FDA
Gastrointestinal

Ototoxicity, Liver Neoplasms, Hepatoblastoma

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