Clinical Trials Browser

Phase 1 × Completed × Hereditary Sensory and Autonomic Neuropathies × Clear all

NCT06308263 2026-04-23

Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303)

Phase 1 Completed

Hereditary Sensory and Autonomic Neuropathies

NCT01226316 2025-06-29

Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

Phase 1 Completed

BreastGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Endometrial Neoplasms

NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

Phase 1 Completed

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT03309150 2024-11-29

ATRi Transition Rollover Study

Phase 1 Completed

1 enrolled 4 charts

Hereditary Sensory and Autonomic Neuropathies

NCT05246111 2024-11-22

Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208)

Phase 1 Completed

6 enrolled 30 charts

Hereditary Sensory and Autonomic Neuropathies

NCT04095273 2024-04-02

Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug

Phase 1 Completed

Ataxia Telangiectasia, Hereditary Sensory and Autonomic Neuropathies

NCT03730142 2023-04-18

A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma

Phase 1 Completed

Hereditary Sensory and Autonomic Neuropathies

NCT02684032 2022-07-27

A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer

Phase 1 Completed

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT00726583 2018-05-17

Phase I Trial of Oral PX-866

Phase 1 Completed

Carcinoma, Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT01470209 2018-03-19

A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies

Phase 1 Completed

Lung Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT01449370 2017-03-09

Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer

Phase 1 Completed

125 enrolled 46 charts

Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT02598570 2017-02-06

Study Evaluating Duvelisib in Japanese Subjects With Relapsed or Refractory Lymphoma

Phase 1 Completed

Lymphoma, Hereditary Sensory and Autonomic Neuropathies