Clinical Trials Browser

OTHER × Interventional × Hereditary Sensory and Autonomic Neuropathies × Clear all

NCT05010031 2026-05-11

A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

Phase 2 Recruiting

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT07522697 2026-04-13

MITO END-4

Phase 2 Not yet recruiting

Hereditary Sensory and Autonomic Neuropathies, Endometrial Neoplasms

NCT02000089 2025-10-09

CAPS5

Phase 3 Recruiting

BreastGastrointestinal

Hereditary pancreatitis, Breast Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Dysplastic Nevus Syndrome, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Peutz-Jeghers Syndrome

NCT04520269 2025-09-25

A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)

Phase 1/2 Active not recruiting

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT02467582 2025-05-16

Adjuvant Aspirin Treatment for Colon Cancer Patients

Phase 3 Terminated

1,040 enrolled 11 charts

Gastrointestinal

Colonic Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT06459193 2025-03-30

Trimetazidine Efficacy in Attenuating Paclitaxel-Induced Peripheral Neuropathy

Phase 1/2 Completed

Hereditary Sensory and Autonomic Neuropathies, Peripheral Nervous System Diseases

NCT02861300 2024-12-19

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

Phase 1/2 Completed

50 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Rectal Neoplasms, Colorectal Neoplasms

NCT04163419 2024-03-13

Phase 2 Study of Tanezumab in Subjects With Moderate to Severe Pain Due to Schwannomatosis

Phase 2 Unknown

Schwannomatosis, Neurilemmoma, Hereditary Sensory and Autonomic Neuropathies, Pain

NCT03318263 2023-08-04

CICLADES

Phase NA Completed

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT05750693 2023-03-02

PIK3CA in HER2+ BC and pCR Trial

Phase NA Unknown

Pathologic Complete Response, Hereditary Sensory and Autonomic Neuropathies

NCT03386162 2022-11-28

SAFIR-PI3K

Phase 2 Terminated

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT04330625 2022-11-08

Glucagon Receptor Inhibition to Enable Breast Cancer Patients to Benefit From PI3K Inhibitor Therapy (REMD-477)

Phase 1 Terminated

Breast Neoplasms, Hyperglycemia, Hereditary Sensory and Autonomic Neuropathies

NCT01276379 2021-07-02

POSIBA

Phase 2 Completed

221 enrolled 17 charts

Gastrointestinal

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies, Colorectal Neoplasms

NCT01942993 2020-09-30

The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma

Phase 2 Terminated

3 enrolled 2 charts

Melanoma, Hereditary Sensory and Autonomic Neuropathies

NCT01640444 2019-04-11

VISNU-2

Phase 2 Completed

Gastrointestinal

Neoplastic Cells, Circulating, Hereditary Sensory and Autonomic Neuropathies, Colorectal Neoplasms

NCT03781050 2019-01-23

Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome

Phase 4 Unknown

Hereditary Sensory and Autonomic Neuropathies, Peutz-Jeghers Syndrome

NCT02644122 2018-07-11

SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway Genes

Phase 2 Terminated

1 enrolled 6 charts

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT01341834 2018-04-24

Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors

Phase 1 Unknown

Head & NeckLymphoid

Nasopharyngeal Carcinoma, Lymphoma, Hereditary Sensory and Autonomic Neuropathies

NCT01470209 2018-03-19

A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies

Phase 1 Completed

Lung Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT01070316 2017-03-13

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

Phase 1/2 Completed

20 enrolled 8 charts

Epilepsy, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT00411619 2014-10-20

Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

Phase 1/2 Completed

28 enrolled 7 charts

Astrocytoma, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT02108769 2014-04-09

Yogic Breathing Changes Salivary Components

Phase NA Completed

Alzheimer Disease, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Neurodegenerative Diseases

NCT00457964 2013-09-25

RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM

Phase 1/2 Completed

Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis, Lymphangioleiomyomatosis