Announcements Trials
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Phase

Phase 2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Myeloid 1Lymphoid 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Follicular 5Sarcoma, Synovial 4Sarcoma 4Rhabdoid Tumor 3Mesothelioma 3Lymphoma, Non-Hodgkin 3Lymphoma, B-Cell 3Recurrence 2Lymphoma, Mantle-Cell 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma 2Wilms Tumor 1Tertiary Lymphoid Structures 1Sarcoma, Ewing 1Rhabdomyosarcoma 1Pancreatic Neoplasms 1Osteosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Medulloblastoma 1Hodgkin Disease 1Histiocytosis, Langerhans-Cell 1Hepatoblastoma 1Hematologic Neoplasms 1Glioma 1Ependymoma 1Colorectal Neoplasms 1Central Nervous System Neoplasms 1

Interventions

thymoglobulin 2fludarabine 2Whole-Body Irradiation 2Tacrolimus 2Rituximab 2Mycophenolic Acid 2Melphalan 2Clofarabine 2Busulfan 2Antilymphocyte Serum 2trametinib 1tazemetostat 1palbociclib 1olaparib 1fludarabine phosphate 1dabrafenib 1X-Rays 1Vemurafenib 1Sunitinib 1Specimen Handling 1Phantoms, Imaging 1Magnetic Resonance Spectroscopy 1LY3023414 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Enzyme-Linked Immunosorbent Assay 1Deferasirox 1Cyclophosphamide 1Cord Blood Stem Cell Transplantation 1CT-P10 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Histiocytosis, Langerhans-Cell × tazemetostat × Clear all
NCT03213665 2026-04-13

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

Phase 2 Completed
20 enrolled 12 charts
CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

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