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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 14Myelodysplastic Syndromes 7Myeloproliferative Disorders 3Myelodysplastic-Myeloproliferative Diseases 2Leukemia, Myelomonocytic, Chronic 2Triple Negative Breast Neoplasms 1Thrombocythemia, Essential 1Primary Myelofibrosis 1Polycythemia Vera 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, B-Cell 1Leukemia, Biphenotypic, Acute 1Hodgkin Disease 1GATA2 Deficiency 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Merkel Cell 1BRCA1 Mutation 1Anemia, Refractory, with Excess of Blasts 1Allogeneic Stem Cell Transplantation 1

Interventions

Cyclophosphamide 11fludarabine phosphate 8Nivolumab 8pembrolizumab 7fludarabine 7Mycophenolic Acid 6Magnetic Resonance Spectroscopy 6Filgrastim 6Doxorubicin 6Dacarbazine 6Brentuximab Vedotin 6Whole-Body Irradiation 5Vinblastine 5Granulocyte Colony-Stimulating Factor 5Cyclosporine 5Specimen Handling 4Melphalan 4Etoposide 4Busulfan 4pegfilgrastim 3Tacrolimus 3Radiotherapy 3Thiotepa 2Sirolimus 2Radiation 2Peripheral Blood Stem Cell Transplantation 2Fluorodeoxyglucose F18 2Cyclosporins 2Clofarabine 2Azacitidine 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Hodgkin Disease × decitabine and cedazuridine drug combination × 30 days × Clear all
NCT05272384 2026-05-13

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

National Cancer Institute (NCI)

Phase 1 Recruiting
32 enrolled
Lymphoid

Hodgkin Disease, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse

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